[一名长期接触有毒化学物质的男性患者的混合性结缔组织病]
[Mixed connective tissue disease in a male patient chronically exposed to toxic chemicals].
作者信息
Panaszek B, Małolepszy J, Wrzyszcz M, Jutel M, Machaj Z
机构信息
Katedry i Kliniki Chorób Wewnetrznych i Alergologii AM we Wrocławiu.
出版信息
Pol Tyg Lek. 1993;48(18-19):430-2.
PMID:8309826
Abstract
A case of the mixed disease of the connective tissue (MCTD) in male patient occupationally exposed to PVC and other toxic agents is presented. Clinical symptoms consisted of the typical signs of SLE, rheumatoid arthritis and lupoid hepatitis. MCTD diagnosis was confirmed serologically by the presence of autoantibodies anti-RNP. Prednisone administered in the daily dose of 60 mg produced remission.
摘要
本文报告一例职业性接触聚氯乙烯及其他有毒物质的男性患者患混合性结缔组织病（MCTD）的病例。临床症状包括系统性红斑狼疮（SLE）、类风湿关节炎和狼疮样肝炎的典型体征。通过抗核糖核蛋白（RNP）自身抗体的存在，血清学确诊为MCTD。每日服用60毫克泼尼松可使病情缓解。
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