Polsinelli V B, Satchidanand N, Singh R, Holmes D, Izzo J L
School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Erie County Medical Center, Buffalo, NY, USA.
J Hum Hypertens. 2017 Feb;31(2):138-144. doi: 10.1038/jhh.2016.52. Epub 2016 Jul 28.
Cross-sectional studies in the developed countries document strong relationships among age, systolic blood pressure (SBP) and pulse pressure (PP). There is little information about these trends and their impact in underdeveloped countries with different socioeconomic and lifestyle characteristics. We studied a convenience sample of 572 residents of rural Fontaine, Haiti: 193 males and 379 females (mean, s.d.) age 40.2 (17.1) years and performed intake questionnaires and BP measurements in participants' homes. Income and educational achievement were very low but most-recommended lifestyle factors were very favorable: very high physical activity, low dietary fat, virtually no obesity (body mass index 21.8 (4.9)), and low smoking prevalence. Rough estimates of salt intake were high (~13 g per day) as was the overall prevalence of hypertension: 34.4% (23.4% in males, 40.2% in females). SBP and PP were related closely to age (r=0.28, P<0.001 and r=0.22, P<0.001); for each decade of age, SBP increased by 7.6 mm Hg. Diastolic BP peaked in the 6th decade (polynomial r=0.22, P<0.001) and the nadir of PP occurred in the 3rd decade. We conclude that, despite a favorable profile of lifestyle characteristics and no obesity, the prevalence of hypertension and rate of increase in SBP and PP with age in Haiti are at least as high as those of developed countries.
发达国家的横断面研究表明,年龄、收缩压(SBP)和脉压(PP)之间存在密切关系。关于这些趋势及其在具有不同社会经济和生活方式特征的欠发达国家中的影响,几乎没有相关信息。我们对海地丰坦农村的572名居民进行了一项便利抽样研究:193名男性和379名女性(均值,标准差),年龄为40.2(17.1)岁,并在参与者家中进行了问卷调查和血压测量。收入和教育水平非常低,但大多数推荐的生活方式因素却非常有利:身体活动量非常高、饮食脂肪含量低、几乎没有肥胖(体重指数为21.8(4.9)),吸烟率也很低。盐摄入量的粗略估计很高(约每天13克),高血压的总体患病率也很高:34.4%(男性为23.4%,女性为40.2%)。收缩压和脉压与年龄密切相关(r = 0.28,P < 0.001;r = 0.22,P < 0.001);每增长十岁,收缩压升高7.6毫米汞柱。舒张压在第六个十年达到峰值(多项式r = 0.22,P < 0.001),脉压最低点出现在第三个十年。我们得出结论,尽管生活方式特征良好且没有肥胖现象,但海地高血压的患病率以及收缩压和脉压随年龄的增长速率至少与发达国家一样高。