Alhawassi T M, Krass I, Pont L G
College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Department of Pharmacy Services, King Saud University Medical City, Riyadh, Saudi Arabia.
Saudi Pharm J. 2017 Dec;25(8):1201-1207. doi: 10.1016/j.jsps.2017.09.004. Epub 2017 Sep 14.
The aim of this study was to explore the prevalence and management of hypertension among older adults on admission to hospital and to assess the choice of antihypertensive pharmacotherapy in light of relevant comorbid conditions using the national treatment guideline.
A retrospective cross sectional study of 503 patients aged 65 years or older admitted to a large metropolitan teaching hospital in Sydney Australia was conducted. The main outcome measures were prevalence of hypertension, blood pressure (BP) control, antihypertensive medication use and the appropriateness of antihypertensive medications.
Sixty-nine percent (n = 347) of the study population had a documented diagnosis of hypertension and of these, approximately one third were at target BP levels on admission to hospital. Some concerns regarding choice of antihypertensive noted with 51% of those with comorbid diabetes and 30% of those with comorbid heart failure receiving a potentially inappropriate antihypertensive agent.
Despite the use of antihypertensive pharmacotherapy, many older adults do not have optimal BP control and are not reaching target BP levels. New strategies to improve blood pressure control in older populations especially targeting women, those with a past history of myocardial infarction and those on multiple antihypertensive medications are needed.
本研究旨在探讨老年住院患者高血压的患病率及管理情况,并根据国家治疗指南,结合相关合并症评估降压药物治疗的选择。
对澳大利亚悉尼一家大型都市教学医院收治的503例65岁及以上患者进行回顾性横断面研究。主要观察指标为高血压患病率、血压(BP)控制情况、降压药物使用情况及降压药物的合理性。
69%(n = 347)的研究人群有高血压确诊记录,其中约三分之一在入院时血压达到目标水平。对于降压药物的选择存在一些担忧,51%的合并糖尿病患者和30%的合并心力衰竭患者接受了可能不适当的降压药物。
尽管使用了降压药物治疗,但许多老年人的血压并未得到最佳控制,未达到目标血压水平。需要制定新的策略来改善老年人群的血压控制,尤其是针对女性、有心肌梗死病史的人群以及使用多种降压药物的人群。