Charrette Ann L, Lorenz Laura S, Fong Jeffrey, O'Neil-Pirozzi Therese M, Lamson Karen, Demore-Taber Michelle, Lilley Ross
a School of Physical Therapy , MCPHS University , Worcester , MA , USA.
b Supportive Living Inc Research Council , Lexington , MA , USA.
Brain Inj. 2016;30(10):1213-9. doi: 10.1080/02699052.2016.1187766. Epub 2016 Jul 28.
Effects of high-intensity exercise on endurance, mobility and gait speed of adults with chronic moderate-to-severe acquired brain injury (ABI) were investigated. It was hypothesized that intensive exercise would be associated with improvements in impairment and activity limitation measures.
Fourteen adults with chronic ABI in supported independent living who could stand with minimal or no assist and walk with or without ambulation device were studied. Eight presented with low ambulatory status.
This was a single group pre- and post-intervention study. Participants received a 6-week exercise intervention for 60-90 minutes, 3 days/week assisted by personal trainers under physical therapist supervision. Measures (6MWT, HiMAT and 10MWT) were collected at baseline, post-intervention and 6 weeks later. Repeated measures T-test and Wilcoxon Signed Ranks test were used.
Post-intervention improvements were achieved on average on all three measures, greater than minimal detectable change (MDC) for this population. Three participants transitioned from low-to-high ambulatory status and maintained the change 6 weeks later.
People with chronic ABI can improve endurance, demonstrate the ability to do advanced gait and improve ambulatory status with 6 weeks of intensive exercise. Challenges to sustainability of exercise programmes for this population remain.
研究高强度运动对患有慢性中度至重度后天性脑损伤（ABI）的成年人的耐力、活动能力和步速的影响。研究假设高强度运动将与损伤和活动受限指标的改善相关。
对14名在支持性独立生活环境中的慢性ABI成年人进行了研究，这些人能够在极少或无辅助的情况下站立，并能使用或不使用步行辅助装置行走。其中8人行走能力较低。
这是一项单组干预前后研究。参与者在物理治疗师的监督下，由私人教练协助进行为期6周的运动干预，每周3天，每次60 - 90分钟。在基线、干预后和6周后收集测量指标（6分钟步行试验、高级运动能力测试和10米步行试验）。使用重复测量T检验和威尔科克森符号秩检验。
干预后，所有三项测量指标平均都有改善，大于该人群的最小可检测变化（MDC）。三名参与者从低行走能力状态转变为高行走能力状态，并在6周后保持了这种变化。
患有慢性ABI的人通过6周的高强度运动可以提高耐力，表现出进行高级步态的能力，并改善行走状态。对于该人群，运动计划的可持续性仍然存在挑战。
