Greenfield Jeffrey P, Castañeda Heredia Alicia, George Emilie, Kieran Mark W, Morales La Madrid Andres
Children's Brain Tumor Project, Department of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Department of Pediatric Hematology and Oncology, Hospital Sant Joan de Deu, Barcelona, Spain.
Pediatr Blood Cancer. 2016 Dec;63(12):2072-2077. doi: 10.1002/pbc.26169. Epub 2016 Jul 28.
Gliomatosis cerebri (GC) is a universally fatal extensive and diffuse infiltration of brain parenchyma by a glial tumor. Many aspects of this phenomenon remain unknown. The First International Gliomatosis cerebri Group Meeting had the following goals: refine the clinical and radiologic diagnostic criteria for GC, suggest appropriate diagnostic procedures, standardize tissue manipulation for histologic and molecular characterization, and prioritize relevant preclinical projects. Also, general treatment recommendations were outlined for the pediatric population. Importantly, this meeting was the starting point for meaningful collaborative international research projects. This review is a consensus summary of discussions shared and conclusions derived from this meeting.
大脑胶质瘤病（GC）是一种由胶质肿瘤广泛弥漫浸润脑实质的普遍致命性疾病。这一现象的许多方面仍不为人知。第一届国际大脑胶质瘤病小组会议有以下目标：完善GC的临床和放射学诊断标准，提出合适的诊断程序，规范用于组织学和分子特征分析的组织处理方法，并确定相关临床前项目的优先顺序。此外，还概述了针对儿童群体的一般治疗建议。重要的是，本次会议是有意义的国际合作研究项目的起点。本综述是本次会议讨论内容和得出结论的共识总结。
