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测量围手术期结果。

Measuring perioperative outcome.

作者信息

Shulman Mark, Myles Paul

机构信息

Department of Anaesthesia and Perioperative Medicine, Alfred Hospital and Monash University, Melbourne, Victoria, Australia.

出版信息

Curr Opin Anaesthesiol. 2016 Dec;29(6):733-738. doi: 10.1097/ACO.0000000000000383.

Abstract

PURPOSE OF REVIEW

Measuring clinically relevant and patient-centered perioperative outcomes provides the knowledge that enables clinicians to optimize their practice and guide shared decision-making, researchers to set a future agenda and policymakers to prioritize healthcare spending.

RECENT FINDINGS

A large international collaboration is currently working to define a set of core outcomes for use in perioperative medicine research. Standardizing which outcomes are measured and how they are defined will help ensure that perioperative research output is meaningful and practice changing. The ability to pool nonheterogeneous data from multiple clinical trials will also improve ability of research to provide definitive answers and improve the cost-effectiveness of research spending.

SUMMARY

Future clinical trials in perioperative medicine should utilize clearly defined, validated and standardized patient-centered outcome measures.

摘要

综述目的

衡量具有临床相关性且以患者为中心的围手术期结局,可为临床医生优化其医疗实践及指导共同决策提供知识依据,为研究人员设定未来议程,也为政策制定者确定医疗保健支出的优先事项提供参考。

最新发现

目前一项大型国际合作正在致力于确定一套用于围手术期医学研究的核心结局指标。对所测量的结局指标及其定义进行标准化,将有助于确保围手术期研究成果具有实际意义并能改变医疗实践。整合来自多个临床试验的非同质化数据的能力,也将提高研究提供明确答案的能力,并提高研究经费的成本效益。

总结

未来围手术期医学的临床试验应采用明确界定、经过验证且标准化的以患者为中心的结局指标。

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