一例具有核型异常的鳞状细胞膀胱癌，其核型异常让人联想到移行细胞癌。
A squamous cell bladder carcinoma with karyotypic abnormalities reminiscent of transitional cell carcinoma.
作者信息
Lundgren R, Elfving P, Heim S, Kristoffersson U, Mandahl N, Mitelman F
机构信息
Department of Clinical Genetics, University Hospital, Lund, Sweden.
出版信息
J Urol. 1989 Aug;142(2 Pt 1):374-6. doi: 10.1016/s0022-5347(17)38765-7.
A squamous cell carcinoma was investigated cytogenetically by means of chromosome banding. The karyotype was complex with many structural and numerical changes, including -9 and del(11p), aberrations that also have been noted in transitional cell carcinoma. Thus, cytogenetic studies may be an important complement to the histological classification of bladder tumors, and may even contribute to our understanding of the etiology and pathogenesis of the 2 main types of bladder cancer.
通过染色体显带技术对一例鳞状细胞癌进行了细胞遗传学研究。其核型复杂，存在许多结构和数量变化，包括 -9 和 del(11p)，这些畸变在移行细胞癌中也有发现。因此，细胞遗传学研究可能是膀胱肿瘤组织学分类的重要补充，甚至可能有助于我们理解两种主要类型膀胱癌的病因和发病机制。
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