Sekiguchi T, Okamoto T, Ohara K, Kohzan S, Nishimori M, Miyazaki M
Department of Pediatrics, Takamatsu Red Cross Hospital.
Jpn J Antibiot. 1989 Mar;42(3):733-42.
Sulbactam/ampicillin (SBT/ABPC) was given intravenously to 20 children with the following acute bacterial infections; 14 cases of pneumonia, 2 cases of purulent cervical lymphadenitis and 1 case each of bronchitis, pyothorax, cellulitis, and purulent meningitis. Good clinical responses were obtained in 18 out of 20 patients, and bacteriologically, all of the 14 isolated strains were eradicated. No side effect was observed except 2 cases of eosinophilia, and 1 case each of loose stool and elevated thrombocyte. From the above clinical results, it is apparent that SBT/ABPC is a useful antibiotic for the treatment of pediatric patients with various kinds of bacterial infections.
对20例患有下列急性细菌感染的儿童静脉注射舒巴坦/氨苄西林（SBT/ABPC）；14例肺炎、2例化脓性颈淋巴结炎、支气管炎、脓胸、蜂窝织炎和化脓性脑膜炎各1例。20例患者中有18例获得了良好的临床反应，从细菌学角度看，14株分离菌株全部被清除。除2例嗜酸性粒细胞增多、1例腹泻和1例血小板升高外，未观察到副作用。从上述临床结果来看，显然SBT/ABPC是治疗患有各种细菌感染的儿科患者的一种有用抗生素。
