Grinberg Lea T, Anghinah Renato, Nascimento Camila Fernandes, Amaro Edson, Leite Renata P, Martin Maria da Graça M, Naslavsky Michel S, Takada Leonel T, Filho Wilson Jacob, Pasqualucci Carlos A, Nitrini Ricardo
Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.
Department of Pathology - LIM-22, University of São Paulo Medical School, São Paulo, Brazil.
J Alzheimers Dis. 2016 Jul 29;54(1):169-74. doi: 10.3233/JAD-160312.
The relationship between soccer and chronic traumatic encephalopathy (CTE) is not well established. We report clinicopathological correlations in an 83-year-old retired center-back soccer player, with no history of concussion, manifesting typical Alzheimer-type dementia. Examination revealed mixed pathology including widespread CTE, moderate Alzheimer's disease, hippocampal sclerosis, and TDP-43 proteinopathy. This case adds to a few CTE cases described in soccer players. Furthermore, it corroborates that CTE may present clinically as typical Alzheimer-type dementia. Further studies investigating the extent to which soccer is a risk for CTE are needed.
足球与慢性创伤性脑病（CTE）之间的关系尚未明确确立。我们报告了一名83岁退休中后卫足球运动员的临床病理相关性，该运动员无脑震荡病史，表现为典型的阿尔茨海默病型痴呆。检查发现混合性病理改变，包括广泛的CTE、中度阿尔茨海默病、海马硬化和TDP-43蛋白病。该病例补充了已报道的少数足球运动员CTE病例。此外，它证实了CTE在临床上可能表现为典型的阿尔茨海默病型痴呆。需要进一步研究以调查足球运动导致CTE的风险程度。
