Sanjuan Pilar M, Poremba Carly, Flynn Lucinda R, Savich Renate, Annett Robert D, Stephen Julia
Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, 2650 Yale Boulevard, SE, MSC11-6280, Albuquerque, NM 87106, USA.
The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, 1101 Yale Blvd, NE, Albuquerque, NM 87106, USA.
Neurosci Lett. 2016 Sep 6;630:120-126. doi: 10.1016/j.neulet.2016.07.048. Epub 2016 Jul 26.
Compared to infants born to mothers without PTSD, infants born to mothers with active PTSD develop poorer behavioral reactivity and emotional regulation. However, the association between perinatal maternal PTSD and infant neural activation remains largely unknown. This pilot study (N=14) examined the association between perinatal PTSD severity and infant frontal neural activity, as measured by MEG theta power during rest. Results indicated that resting left anterior temporal/frontal theta power was correlated with perinatal PTSD severity (p=0.004). These findings suggest delayed cortical maturation in infants whose mothers had higher perinatal PTSD severity and generate questions regarding perinatal PTSD severity and infant neurophysiological consequences.
与母亲没有创伤后应激障碍(PTSD)的婴儿相比,母亲患有活动性PTSD的婴儿行为反应性和情绪调节能力较差。然而,围产期母亲PTSD与婴儿神经激活之间的关联在很大程度上仍不清楚。这项试点研究(N = 14)通过静息状态下的脑磁图(MEG)θ波功率测量,研究了围产期PTSD严重程度与婴儿额叶神经活动之间的关联。结果表明,静息状态下左侧颞叶前部/额叶的θ波功率与围产期PTSD严重程度相关(p = 0.004)。这些发现表明,母亲围产期PTSD严重程度较高的婴儿存在皮质成熟延迟,并引发了关于围产期PTSD严重程度和婴儿神经生理后果的问题。