Department of Psychology, Emory University, Atlanta, GA, 30322.
Dev Psychobiol. 2014 Apr;56(3):459-73. doi: 10.1002/dev.21112. Epub 2013 Jul 12.
Electroencephalogram (EEG) patterns may reflect a vulnerability to depression. In an effort to understand their earliest origin, we examined their stability and consistency and their associations with perinatal depressive symptoms. Depressive symptoms were measured prospectively throughout the perinatal period in 83 women with histories of depression and/or anxiety. Infant's EEG was recorded during baseline, feeding, and play at 3 and 6 months of age. Prenatal and postpartum depressive symptoms interacted significantly to predict 3- and 6-month-olds' EEG asymmetry scores. Asymmetry scores were consistent across contexts, except from baseline to feeding and play at 6 months, and stable across ages, except during feeding. Changes in depressive symptoms across ages were not associated with changes in infant EEG. Findings highlight the importance of considering both prenatal and postpartum depressive symptoms in the prediction of infant EEG, as well as the need to consider context to understand stability of infant EEG patterns.
脑电图 (EEG) 模式可能反映出对抑郁症的易感性。为了了解其最早的起源，我们研究了它们的稳定性和一致性，以及它们与围产期抑郁症状的关联。在 83 名有抑郁和/或焦虑病史的女性中，前瞻性地在围产期全程测量抑郁症状。在婴儿 3 个月和 6 个月大时，记录他们的脑电图，分别在基线、进食和玩耍时进行记录。产前和产后抑郁症状显著相互作用，预测 3 个月和 6 个月大婴儿的脑电图不对称评分。除了 6 个月大时从基线到进食和玩耍的情况外，不对称评分在各个情境下都是一致的，而且在各个年龄段都是稳定的，除了进食时。随着年龄的变化，抑郁症状的变化与婴儿脑电图的变化无关。研究结果强调了在预测婴儿脑电图时既要考虑产前和产后抑郁症状，又要考虑到理解婴儿脑电图模式稳定性时需要考虑情境的重要性。
