Gilles de la Tourette综合征——一种可治疗的疾病？
Gilles de la Tourette syndrome - A treatable condition?
作者信息
Hartmann A, Martino D, Murphy T
机构信息
Sorbonne universités, UPMC univeristé Paris 06, UMR S 1127, CNRS UMR 7225, ICM, 75013 Paris, France; Department of neurology, groupe hospitalier Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47, boulevard de l'Hôpital, 75013 Paris, France; French National Reference Centre for Gilles de la Tourette Syndrome, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
International Parkinson's Centre of Excellence, King's College and King's College Hospital, Denmark Hill Campus, London, UK; Queen Elizabeth Hospital, Woolwich, Lewisham & Greenwich NHS Trust, London, UK.
出版信息
Rev Neurol (Paris). 2016 Aug-Sep;172(8-9):446-454. doi: 10.1016/j.neurol.2016.07.004. Epub 2016 Jul 28.
INTRODUCTION
Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder characterized by chronic motor and vocal tics. Psychiatric comorbidity is frequent but does not enter into the official classification of the syndrome. In the present article, we will focus on treatment options for tics.
METHODS
We have reviewed the relevant literature on treatment of tics and GTS, especially in the period from 2011-2016 since the publication of the European Society for the Study of Tourette Syndrome (ESSTS) treatment guidelines in 2011.
RESULTS
We present current and up-to-date approaches in psychotherapy, pharmacotherapy and neurosurgery for GTS with an outlook for the upcoming years.
CONCLUSIONS
Although many patients and health-care professionals seem to view tics and/or GTS as difficult to treat, or believe that treatment requires severe side effects with reduction in quality of life, we wish to convey that there is cause for optimism, both with regard to available treatment modalities and future therapeutic developments.
引言
抽动秽语综合征（GTS）是一种神经发育障碍，其特征为慢性运动性和发声性抽动。精神共病很常见，但并不纳入该综合征的官方分类。在本文中，我们将聚焦于抽动的治疗选择。
方法
我们回顾了关于抽动和GTS治疗的相关文献，特别是自2011年欧洲抽动秽语综合征研究学会（ESSTS）治疗指南发布以来的2011 - 2016年期间的文献。
结果
我们介绍了目前针对GTS的心理治疗、药物治疗和神经外科治疗的最新方法，并展望了未来几年的发展。
结论
尽管许多患者和医疗保健专业人员似乎认为抽动和/或GTS难以治疗，或者认为治疗会带来严重副作用并降低生活质量，但我们希望传达的是，无论是对于现有的治疗方式还是未来的治疗发展，都有理由保持乐观。
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