Zakaria Ali, Al-Share Bayan, Al Asad Khaled
Istishari Hospital, Department of Internal Medicine, Division of Pulmonology, Amman 11183, Jordan.
Case Rep Pulmonol. 2016;2016:8709347. doi: 10.1155/2016/8709347. Epub 2016 Jul 10.
Amebiasis is a parasitic infection caused by the protozoan Entamoeba histolytica. While most infections are asymptomatic, the disease could manifest clinically as amebic dysentery and/or extraintestinal invasion in the form of amebic liver abscess or other more rare manifestations such as pulmonary, cardiac, or brain involvement. Herein we are reporting a case of a 24-year-old male with history of Down syndrome who presented with severe right side pneumonia complicated with multicystic empyema resistant to regular medical therapy. Further investigation revealed a positive pleural fluid for E. histolytica cysts and trophozoites. The patient was diagnosed with primary pleuropulmonary amebiasis and he responded promptly to surgical drainage and metronidazole therapy. In patients from endemic areas all physicians should keep a high index of suspicion of amebiasis as a cause of pulmonary disease.
阿米巴病是由原生动物溶组织内阿米巴引起的寄生虫感染。虽然大多数感染是无症状的，但该疾病临床上可能表现为阿米巴痢疾和/或以阿米巴肝脓肿形式出现的肠外侵袭，或其他更罕见的表现，如肺部、心脏或脑部受累。在此，我们报告一例24岁患有唐氏综合征的男性患者，该患者出现严重的右侧肺炎并伴有对常规药物治疗耐药的多囊性脓胸。进一步检查发现胸腔积液中溶组织内阿米巴囊肿和滋养体呈阳性。该患者被诊断为原发性胸膜肺阿米巴病，他对手术引流和甲硝唑治疗反应迅速。对于来自流行地区的患者，所有医生都应高度怀疑阿米巴病是肺部疾病的病因。
