Department of Electronic Engineering, Information School, Yunnan University, Kunming, Yunnan 650091, China; School of Computer and Information, Southwest Forestry University, Kunming, Yunnan 650224, China.
Department of Electronic Engineering, Information School, Yunnan University, Kunming, Yunnan 650091, China.
Biomed Res Int. 2016;2016:8502873. doi: 10.1155/2016/8502873. Epub 2016 Jul 10.
This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of blood flow field modulated by wall motion. This model takes into account fluid-structure interaction, blood pulsatility, stenosis of the vessel, and arterial wall movement caused by surrounding tissue's motion. The axial and radial velocity distributions of blood and the displacement of vessel wall are calculated by solving coupled Navier-Stokes and wall equations. With these obtained values, we made several different phantoms by treating blood and the vessel wall as a group of point scatterers. Then, ultrasound echoed signals from oscillating wall and blood in the axisymmetric stenotic-carotid arteries were computed by ultrasound simulation software, Field II. The results show better consistency with corresponding theoretical values and clinical data and reflect the influence of wall movement on the flow field. It can serve as an effective tool not only for investigating the behavior of blood flow field modulated by wall motion but also for quantitative or qualitative evaluation of new ultrasound imaging technology and estimation method of blood velocity.
本文提出了一种基于狭窄血管壁运动调制的脉动血流超声模拟模型。旨在生成更真实的超声信号,为超声信号处理和成像的评估提供环境,并为研究壁运动调制下血流场的行为提供框架。该模型考虑了流固耦合、血液脉动、血管狭窄以及周围组织运动引起的血管壁位移。通过求解耦合的纳维-斯托克斯方程和壁方程,计算血液的轴向和径向速度分布以及血管壁的位移。根据这些计算值,我们通过将血液和血管壁视为一组点散射体来制作几个不同的模型。然后,通过超声模拟软件 Field II 计算了轴对称狭窄颈动脉中振荡壁和血液的超声回波信号。结果与相应的理论值和临床数据具有更好的一致性,反映了壁运动对流场的影响。它不仅可以作为研究壁运动调制下血流场行为的有效工具,还可以用于新的超声成像技术的定量或定性评估以及血流速度估计方法。