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75岁以上患者单髁膝关节置换术与全膝关节置换术相比,临床疗效更好,假体生存率相似。一项配对对照研究。

Unicompartmental Knee Arthroplasty in Patients Older Than 75 Results in Better Clinical Outcomes and Similar Survivorship Compared to Total Knee Arthroplasty. A Matched Controlled Study.

作者信息

Fabre-Aubrespy Maxime, Ollivier Matthieu, Pesenti Sébastien, Parratte Sébastien, Argenson Jean-Noël

机构信息

Department of Orthopedics and Traumatology, St. Marguerite Hospital, Marseille, France.

出版信息

J Arthroplasty. 2016 Dec;31(12):2668-2671. doi: 10.1016/j.arth.2016.06.034. Epub 2016 Jun 29.

Abstract

BACKGROUND

Due to the potential reduction of morbidity and mortality, unicompartmental knee arthroplasty (UKA) may represent an interesting solution for older patients with unicompartmental arthritis. It was our hypothesis that UKA can represent an alternative to total knee arthroplasty (TKA) for patients older than 75. We, thus, aimed to compare in those patients (1) functional results, (2) rates of forgotten joint, and (3) survivorships of UKA vs TKA.

METHODS

In this retrospective matched-pair study, 101 patients who underwent UKA in our institution were included and then matched one-to-one with TKA group based on age, gender, body mass index, preoperative Knee Society Score (KSS). Inclusion criteria were age between 75 and 90 years on the day of surgery, knee arthroplasty performed for primary osteoarthritis or osteonecrosis of the knee. All patients were evaluated clinically (using KSS, Knee Injury Osteoarthritis Outcome Score [KOOS], and Forgotten Joint Score) at 1, 2, and every 5 years, thereafter. Survivorships of UKA and TKA implants were also compared.

RESULTS

At last follow-up, patients from UKA group had better KSS than in TKA group, (respectively, KSS function 82.8 ± 12.2 vs 79.2 ± 13.1 [P = .0448] and KSS knee 88.2 ± 8.9 vs 82.3 ± 12.5 [P = .0005]). Knee Injury Osteoarthritis Outcome Scores were also higher in UKA group (all P < .001) as well as the rate of forgotten knees (42% vs 25% P = .01). Sixteen-year survivorships free from revision for any reason were similar in the 2 groups (91.8% vs 94.6% P = .66).

CONCLUSION

The results of our study showed that UKA provide higher function and better forgotten joint scores with similar survivorship, compared to TKA, for patients older than 75.

摘要

背景

由于单髁膝关节置换术(UKA)可能降低发病率和死亡率,对于患有单髁关节炎的老年患者而言,它可能是一种理想的治疗方案。我们的假设是,对于75岁以上的患者,UKA可以替代全膝关节置换术(TKA)。因此,我们旨在比较这些患者中(1)功能结果、(2)遗忘关节发生率以及(3)UKA与TKA的生存率。

方法

在这项回顾性配对研究中,纳入了在我们机构接受UKA的101例患者,然后根据年龄、性别、体重指数、术前膝关节协会评分(KSS)与TKA组进行一对一配对。纳入标准为手术当天年龄在75至90岁之间,因原发性骨关节炎或膝关节骨坏死而进行膝关节置换术。所有患者在术后1年、2年及之后每5年进行临床评估(使用KSS、膝关节损伤骨关节炎结局评分[KOOS]和遗忘关节评分)。还比较了UKA和TKA植入物的生存率。

结果

在最后一次随访时,UKA组患者的KSS优于TKA组(分别为,KSS功能82.8±12.2对79.2±13.1[P = 0.0448],KSS膝关节88.2±8.9对82.3±12.5[P = 0.0005])。UKA组的膝关节损伤骨关节炎结局评分也更高(所有P < 0.001),以及遗忘膝关节的发生率(42%对25%,P = 0.01)。两组因任何原因无需翻修的16年生存率相似(91.8%对94.6%,P = 0.66)。

结论

我们的研究结果表明,对于75岁以上的患者,与TKA相比,UKA具有更高的功能和更好的遗忘关节评分,且生存率相似。

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