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Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR).发展中国家地中海贫血患者铁定量的超快磁共振成像:TIC-TOC研究(泰国和英国地中海贫血超快CMR优化国际合作)
Circulation. 2016 Aug 2;134(5):432-4. doi: 10.1161/CIRCULATIONAHA.116.022803.
2
Quantitative MRI evaluation of iron deposition in patients with transfusion-dependent thalassemia: clinical management insights.输血依赖型地中海贫血患者铁沉积的定量MRI评估:临床管理见解
Expert Rev Hematol. 2024 Dec;17(12):977-983. doi: 10.1080/17474086.2024.2435353. Epub 2024 Dec 3.
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Increased sympathovagal imbalance evaluated by heart rate variability is associated with decreased T2* MRI and left ventricular function in transfusion-dependent thalassemia patients.心率变异性评估的交感神经迷走神经失衡与依赖输血的地中海贫血患者的 T2*MRI 降低和左心室功能下降有关。
Biosci Rep. 2018 Feb 2;38(1). doi: 10.1042/BSR20171266. Print 2018 Feb 28.
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What is the importance of monitoring iron levels in different organs over time with magnetic resonance imaging in transfusion-dependent thalassemia patients?对于依赖输血的地中海贫血患者,随着时间推移通过磁共振成像监测不同器官中铁含量的重要性是什么?
Expert Rev Hematol. 2025 Apr;18(4):291-299. doi: 10.1080/17474086.2025.2486379. Epub 2025 Mar 31.
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Application of the magnetic resonance 3D multiecho Dixon sequence for quantifying hepatic iron overload and steatosis in patients with thalassemia.磁共振 3D 多回波 Dixon 序列在铁过载和脂肪变性定量分析地中海贫血患者肝脏中的应用。
Magn Reson Imaging. 2024 Sep;111:28-34. doi: 10.1016/j.mri.2024.03.015. Epub 2024 Mar 15.
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Organ-Specific Iron Overload in Non-Transfusion-Dependent Thalassemia Patients: Insights from Quantitative MRI Evaluation.非输血依赖型地中海贫血患者的器官特异性铁过载:定量MRI评估的见解
Eur J Radiol. 2024 Dec;181:111750. doi: 10.1016/j.ejrad.2024.111750. Epub 2024 Oct 10.
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Extreme cardiac iron loading in transfusion-dependent thalassaemia major: cardiac T2* and T1 mapping guiding treatment.重型输血依赖型地中海贫血的严重心脏铁过载:心脏T2*和T1成像指导治疗
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Absence of cardiac siderosis despite hepatic iron overload in Italian patients with thalassemia intermedia: an MRI T2* study.意大利中间型地中海贫血患者存在肝脏铁过载但无心脏铁沉积:一项 MRI T2*研究。
Ann Hematol. 2010 Jun;89(6):585-9. doi: 10.1007/s00277-009-0879-3. Epub 2009 Dec 17.
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Future challenges in the use of magnetic resonance imaging for the diagnosis of iron overload.磁共振成像用于诊断铁过载的未来挑战。
Blood Transfus. 2010 Oct;8(4):309-10. doi: 10.2450/2010.0017-10.
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Evaluation of myocardial iron overload using magnetic resonance imaging.使用磁共振成像评估心肌铁过载。
Blood Transfus. 2009 Jul;7(3):183-7. doi: 10.2450/2008.0063-08.

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Assessing Acute Pericarditis with T1 Mapping: A Supportive Contrast-Free CMR Marker.采用T1映射评估急性心包炎:一种无需造影剂的CMR支持性标志物。
Tomography. 2024 Nov 27;10(12):1881-1894. doi: 10.3390/tomography10120137.
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Atrial and ventricular strain using cardiovascular magnetic resonance in the prediction of outcomes of pericarditis patients: a pilot study.心血管磁共振测量心房和心室应变在预测心包炎患者转归中的应用:一项初步研究。
Eur Radiol. 2024 Sep;34(9):5724-5735. doi: 10.1007/s00330-024-10677-9. Epub 2024 Mar 11.
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Atrial and Ventricular Strain Imaging Using CMR in the Prediction of Ventricular Arrhythmia in Patients with Myocarditis.使用心脏磁共振成像进行心房和心室应变成像在预测心肌炎患者室性心律失常中的应用
J Clin Med. 2024 Jan 23;13(3):662. doi: 10.3390/jcm13030662.
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Improving cardiovascular magnetic resonance access in low- and middle-income countries for cardiomyopathy assessment: rapid cardiovascular magnetic resonance.改善中低收入国家心血管磁共振检查以评估心肌病:快速心血管磁共振成像。
Eur Heart J. 2022 Jul 7;43(26):2496-2507. doi: 10.1093/eurheartj/ehac035.
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Effective Study: Development and Application of a Question-Driven, Time-Effective Cardiac Magnetic Resonance Scanning Protocol.有效学习:问题驱动的、省时的心脏磁共振扫描方案的开发和应用。
J Am Heart Assoc. 2022 Jan 4;11(1):e022605. doi: 10.1161/JAHA.121.022605. Epub 2021 Dec 31.
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Use of rapid cardiac magnetic resonance imaging to guide chelation therapy in patients with transfusion-dependent thalassaemia in India: UMIMI study.使用快速心脏磁共振成像指导印度输血依赖型地中海贫血患者的螯合治疗:UMIMI 研究。
Eur Heart J Qual Care Clin Outcomes. 2022 May 5;8(3):289-297. doi: 10.1093/ehjqcco/qcab089.
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Cardiac T2 star mapping: standardized inline analysis of long and short axis at three identical 1.5 T MRI scanners.心脏T2* 成像:在三台相同的1.5T磁共振成像扫描仪上对长轴和短轴进行标准化在线分析。
Int J Cardiovasc Imaging. 2019 Apr;35(4):695-702. doi: 10.1007/s10554-018-1503-1. Epub 2018 Nov 21.
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INCA (Peru) Study: Impact of Non-Invasive Cardiac Magnetic Resonance Assessment in the Developing World.INCA(秘鲁)研究:无创性心脏磁共振评估在发展中国家的影响。
J Am Heart Assoc. 2018 Sep 4;7(17):e008981. doi: 10.1161/JAHA.118.008981.
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Potential for Rapid and Cost-Effective Cardiac Magnetic Resonance in the Developing (and Developed) World.发展中(及发达)世界实现快速且具成本效益的心脏磁共振成像的潜力。
J Am Heart Assoc. 2018 Sep 4;7(17):e010435. doi: 10.1161/JAHA.118.010435.
10
Role of T1 mapping as a complementary tool to T2* for non-invasive cardiac iron overload assessment.T1 映射作为 T2* 的补充工具在无创性心脏铁过载评估中的作用。
PLoS One. 2018 Feb 21;13(2):e0192890. doi: 10.1371/journal.pone.0192890. eCollection 2018.

本文引用的文献

1
A medical device-grade T1 and ECV phantom for global T1 mapping quality assurance-the T Mapping and ECV Standardization in cardiovascular magnetic resonance (T1MES) program.用于全球T1映射质量保证的医疗设备级T1和ECV体模——心血管磁共振成像中的T映射与ECV标准化(T1MES)项目
J Cardiovasc Magn Reson. 2016 Sep 22;18(1):58. doi: 10.1186/s12968-016-0280-z.
2
Thalassaemia.地中海贫血症。
Lancet. 2012 Jan 28;379(9813):373-83. doi: 10.1016/S0140-6736(11)60283-3. Epub 2011 Sep 9.
3
On T2* magnetic resonance and cardiac iron.T2* 磁共振与心脏铁沉积
Circulation. 2011 Apr 12;123(14):1519-28. doi: 10.1161/CIRCULATIONAHA.110.007641. Epub 2011 Mar 28.
4
Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload.心血管T2*(T2*)磁共振成像用于心肌铁过载的早期诊断。
Eur Heart J. 2001 Dec;22(23):2171-9. doi: 10.1053/euhj.2001.2822.

Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR).

作者信息

Abdel-Gadir Amna, Vorasettakarnkij Yongkasem, Ngamkasem Hataichanok, Nordin Sabrina, Ako Emmanuel A, Tumkosit Monravee, Sucharitchan Pranee, Uaprasert Noppacharn, Kellman Peter, Piechnik Stefan K, Fontana Marianna, Fernandes Juliano L, Manisty Charlotte, Westwood Mark, Porter John B, Walker J Malcolm, Moon James C

机构信息

From Institute of Cardiovascular Science, University College London, UK (A.A.-G., S.N., E.A.A., M.F., C.M., J.M.W., J.C.M.);Barts Heart Centre, London, UK (A.A.-G., S.N., E.A.A., C.M., M.W., J.C.M.); Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); King Chulalongkorn Memorial Hospital, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); Queen Savang Vadhana Memorial Hospital, Sriracha, Thailand (H.N.); Medical Signal and Image Processing Program, National Heart, Lung, and Blood Institute, Bethesda, MD (P.K.); University of Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, UK (S.K.P.); National Amyloidosis Centre, Royal Free Hospital, London, UK (M.F.); Cardiovascular Imaging Center, Jose Michel Kalaf Research Institute, Sao Paulo, Brazil (J.L.F.); Haematology Department, University College London Hospitals, UK (J.B.P.); and Hatter Cardiovascular Institute, University College Hospital, London, UK (J.M.W.).

出版信息

Circulation. 2016 Aug 2;134(5):432-4. doi: 10.1161/CIRCULATIONAHA.116.022803.

DOI:10.1161/CIRCULATIONAHA.116.022803
PMID:27482005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4966915/
Abstract
摘要