Fatica N S, Ichida F, Engle M A, Lesser M L
Division of Pediatric Cardiology, New York Hospital-Cornell University Medical Center, New York 10021.
Pediatrics. 1989 Aug;84(2):231-4.
Following personal interviews with 63 families of children with Kawasaki disease and with 63 control families with children paired for race, sex, and age, no epidemiologic differences were seen except for use of rug shampoo within 1 month of onset in 16 episodes in 15 children with Kawasaki disease in 14 families (24% of children, 22% of families) compared with two families of control children (3%, P less than .005). Explanations for this strong association of recent rug shampoo and Kawasaki disease include the question of recall bias as well as the possibility that an agent in the shampooing process does cause or does contribute to illness.
在对63名川崎病患儿的家庭以及63名与之种族、性别和年龄相匹配的对照儿童家庭进行个人访谈后，未发现流行病学差异，只是在14个家庭中，15名川崎病患儿中有16例在发病后1个月内使用过地毯清洁剂（占患儿的24%，家庭的22%），而对照儿童家庭只有2个（3%，P<0.005）。近期使用地毯清洁剂与川崎病之间这种强烈关联的解释包括回忆偏倚问题，以及洗发过程中的某种成分确实导致或促成疾病的可能性。
