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颈部异位微结节性胸腺瘤伴淋巴样间质:1例与朗格汉斯细胞增殖相关的罕见病例

Ectopic micronodular thymoma with lymphoid stroma in the cervical region: a rare case associated with Langerhans cells proliferation.

作者信息

Yu Min, Meng Yuan, Xu Bin, Zhao Lin, Zhang Qingfu

机构信息

Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang, People's Republic of China.

Department of Pathology, Fushun Central Hospital, Fushun, People's Republic of China.

出版信息

Onco Targets Ther. 2016 Jul 18;9:4317-22. doi: 10.2147/OTT.S110802. eCollection 2016.

Abstract

Micronodular thymoma (MNT) with lymphoid stroma is a rare thymic epithelial neoplasm with the characteristics of multiple nodules separated by abundant lymphoid stroma. MNTs mainly arise in the anterior mediastinum and thymus, while ectopic MNTs are extremely rarely seen. Here, we report an ectopic MNT that occurred in the neck of a 62-year-old woman. There were also scattered eosinophilic granulocytes and S100(+)/CD1a(+) Langerhans cells within the tumor. This case provides a better understanding of such rare, poorly understood cases.

摘要

伴有淋巴样间质的微结节型胸腺瘤(MNT)是一种罕见的胸腺上皮性肿瘤,其特征为多个结节被丰富的淋巴样间质分隔。MNT主要发生在前纵隔和胸腺,而异位MNT极为罕见。在此,我们报告一例发生在一名62岁女性颈部的异位MNT。肿瘤内还散在有嗜酸性粒细胞和S100(+)/CD1a(+)朗格汉斯细胞。该病例有助于更好地了解此类罕见且了解甚少的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ded/4958359/163b043be837/ott-9-4317Fig1.jpg

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