Pourriahi Mahyar, Gurman Pablo, Daich Jonathan, Cynamon Philip, Richler Aaron, Elman Noel, Rosen Yitzhak
a Superior Nano Biosystems LLC , Highland Park , NJ , USA.
b Department of Materials Science and Engineering , University of Texas- Dallas , Richardson , Texas , USA.
Expert Rev Med Devices. 2016 Sep;13(9):831-7. doi: 10.1080/17434440.2016.1207520. Epub 2016 Aug 3.
BioMEMS relates to the implementation of Micro-Electro-Mechanical Systems (MEMS), in the biological and medical sphere. BioMEMS sensors are being utilized for many clinical applications, including a wireless urinary pressure system, right heart pressure sensor, and measurements on shearing force on the vascular system An important application of BioMEMS is on Heart failure (HF), a common disease, with a prevalence of 10% or more in persons 70 years of age or older, associated with high morbidity and mortality. HF affects over 5 million people and contributes to over 200,000 deaths a year in the United States alone.
The purpose of this paper is to provide a short overview on the successful implementation of BioMEMS sensors in heart failure and vascular medicine. Expert commentary: BioMEMS devices have overcome current limitations in pharmacotherapies for resistant hypertension by electrical modulation of the baroreceeptors. This represents a step towards the development of biomedical micro-devices for those conditions in which pharmacotherapies result poorly effective or elicit unacceptable toxicity.
生物微机电系统涉及微机电系统（MEMS）在生物和医学领域的应用。生物微机电系统传感器正被用于许多临床应用，包括无线尿压系统、右心压力传感器以及血管系统剪切力测量。生物微机电系统的一个重要应用是针对心力衰竭（HF），这是一种常见疾病，在70岁及以上人群中的患病率达10%或更高，具有高发病率和死亡率。仅在美国，心力衰竭就影响着超过500万人，每年导致超过20万人死亡。
本文旨在简要概述生物微机电系统传感器在心力衰竭和血管医学中的成功应用。专家评论：生物微机电系统装置通过对压力感受器进行电调制，克服了当前抗高血压药物治疗的局限性。这代表着朝着为那些药物治疗效果不佳或引发不可接受毒性的病症开发生物医学微装置迈出了一步。
