Guttier Marília Cruz, Silveira Marysabel Pinto Telis, Luiza Vera Lucia, Bertoldi Andréa Dâmaso
Programa de Pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brasil.
Instituto de Biologia, Universidade Federal de Pelotas, Pelotas, Brasil.
Cad Saude Publica. 2016 Aug 1;32(7). doi: 10.1590/0102-311X00070215.
This study compared the perception, knowledge, and use of generic drugs by adults in Pelotas, Rio Grande do Sul State, Brazil, using two cross-sectional population-based studies from 2002 and 2012. Study outcomes were: (a) prevalence of use of generics; (b) generics as a proportion of all medication; (c) users' perceptions of prices and quality; (d) users' knowledge of generics; and (e) strategies for acquisition of medicines. Prevalence of generics use increased from 3.6% (95%CI: 3.0-4.3) to 26.1% (95%CI: 24.5-27.7) in the 10-year period. Perceptions of prices and quality of generics remained stable, identification of characteristics that distinguish generics from other drugs improved (p < 0.001), and drug classification errors decreased (p < 0.001). There was a significant increase in acquiring medication by replacing prescribed drugs with generics. Between 2002 and 2012 there was an increase in knowledge and use of generics, while perception of lower prices and equivalent quality remained high.
本研究利用2002年和2012年两项基于人群的横断面研究，比较了巴西南里奥格兰德州佩洛塔斯成年人对仿制药的认知、知识和使用情况。研究结果包括：（a）仿制药的使用 prevalence；（b）仿制药在所有药物中所占的比例；（c）使用者对价格和质量的认知；（d）使用者对仿制药的知识；以及（e）购药策略。在这10年期间，仿制药的使用 prevalence 从3.6%（95%CI：3.0 - 4.3）增至26.1%（95%CI：24.5 - 27.7）。对仿制药价格和质量的认知保持稳定，区分仿制药与其他药物的特征识别有所改善（p < 0.001），药物分类错误减少（p < 0.001）。用仿制药替代处方药购药的情况显著增加。2002年至2012年期间，对仿制药的知识和使用有所增加，而对较低价格和同等质量的认知仍然很高。
