Guttier Marília Cruz, Silveira Marysabel Pinto Telis, Luiza Vera Lucia, Bertoldi Andréa Dâmaso
Curso de Farmácia. Centro de Ciências Químicas, Farmacêuticas e de Alimentos. Universidade Federal de Pelotas. Pelotas, RS, Brasil.
Departamento de Fisiologia e Farmacologia, Instituto de Biologia. Universidade Federal de Pelotas. Pelotas, RS, Brasil.
Rev Saude Publica. 2017 Jun 26;51:59. doi: 10.1590/S1518-8787.2017051006786.
The objective of this study is to identify factors associated with the preference for purchasing generic drugs in a medium-sized municipality in Southern Brazil.
We have analyzed data from a population-based cross-sectional study conducted in 2012 with a sample of 2,856 adults (≥ 20 years old). The preference for purchasing generic drugs was the main outcome. The explanatory variables were the demographic and socioeconomic variables. Statistical analyses included Poisson regressions.
The preference for purchasing generic drugs was 63.2% (95%CI 61.4-64.9). The variables correlated with this preference in the fully adjusted models were: male (prevalence ratio [PR] = 1.08; 95%CI 1.03-1.14), age of 20-39 years (PR = 1.10; 95%CI 1.02-1.20), low socioeconomic status (PR = 1.15; 95%CI 1.03-1.28), and good knowledge about generic drugs (PR= 4.66; 95%CI 2.89-7.52). Among those who preferred to purchase generic drugs, 55.1% have reported accepting to replace the prescribed drug (if not a generic) with the equivalent generic drug. Another correlate of the preference for purchasing generic drugs was because individuals consider their quality equivalent to reference medicines (PR = 2.15; 95%CI 1.93-2.41).
Knowledge about generic drugs was the main correlate of the preference for purchasing generic drugs. The greater the knowledge or positive perception about generic drugs, the greater is the preference to purchase them. Therefore, educational campaigns for healthcare professionals and consumers appear to be the best strategy for expanding the use of generic drugs in Brazil.
本研究旨在确定巴西南部一个中等规模城市中与购买非专利药偏好相关的因素。
我们分析了2012年开展的一项基于人群的横断面研究数据,样本为2856名成年人(≥20岁)。购买非专利药的偏好是主要结果。解释变量为人口统计学和社会经济变量。统计分析包括泊松回归。
购买非专利药的偏好为63.2%(95%置信区间61.4 - 64.9)。在完全调整模型中与该偏好相关的变量有:男性(患病率比[PR]=1.08;95%置信区间1.03 - 1.14)、20 - 39岁年龄组(PR = 1.10;95%置信区间1.02 - 1.20)、社会经济地位低(PR = 1.15;95%置信区间1.03 - 1.28)以及对非专利药有良好了解(PR = 4.66;95%置信区间2.89 - 7.52)。在那些更愿意购买非专利药的人群中,55.1%的人表示愿意接受用等效的非专利药替代处方药物(如果不是非专利药)。购买非专利药偏好的另一个相关因素是个人认为其质量等同于参比药品(PR = 2.15;95%置信区间1.93 - 2.41)。
对非专利药的了解是购买非专利药偏好的主要相关因素。对非专利药的了解或积极认知程度越高,购买它们的偏好就越大。因此,针对医疗保健专业人员和消费者开展教育活动似乎是在巴西扩大非专利药使用的最佳策略。