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翼管神经切断术治疗鼻炎的循证医学系统评价

A systematic review of the evidence base for vidian neurectomy in managing rhinitis.

作者信息

Marshak T, Yun W K, Hazout C, Sacks R, Harvey R J

机构信息

Rhinology and Skull Base,Applied Medical Research Centre,University of New South Wales,Sydney,Australia.

Department of Otolaryngology,Head and Neck Surgery,Concord General Hospital,University of Sydney,Australia.

出版信息

J Laryngol Otol. 2016 Jul;130 Suppl 4:S7-S28. doi: 10.1017/S0022215116008008.

Abstract

BACKGROUND

Vidian neurectomy has been proposed as a surgical option for rhinitis refractory to medical treatment. However, the evidence base for its benefit remains controversial.

METHODS

A systematic review was performed. Studies reporting original data on patients with rhinitis treated by vidian neurectomy were included. Patient-reported outcome measures were the primary outcome investigated; specific peri-operative morbidities were the secondary outcome.

RESULTS

A total of 1012 articles fulfilled the search criteria, 32 of which were included in the study. Patient-reported outcome measures were compared before and after surgery in eight studies. There were 529 patients represented in these trials. Significant improvement in rhinorrhoea was reported in all eight studies. Temporary dry eyes was reported in 24.63 per cent of cases (272 out of 1104 cases). There was no report of cranial nerve deficit or eye movement disturbance.

CONCLUSION

Endoscopic vidian neurectomy does have a role in the surgical management of refractory rhinitis, particularly in patients with non-allergic rhinitis, but a well-designed cohort trial would be advantageous to clarify long-term outcomes.

摘要

背景

岩浅大神经切断术已被提议作为药物治疗无效的鼻炎的一种手术选择。然而,其益处的证据基础仍存在争议。

方法

进行了一项系统评价。纳入报告经岩浅大神经切断术治疗的鼻炎患者原始数据的研究。患者报告的结局指标是主要研究结局;特定的围手术期发病率是次要结局。

结果

共有1012篇文章符合检索标准,其中32篇被纳入研究。八项研究比较了手术前后患者报告的结局指标。这些试验中有529名患者。所有八项研究均报告鼻漏有显著改善。24.63%的病例(1104例中的272例)报告有暂时性干眼。未报告有颅神经缺损或眼球运动障碍。

结论

内镜下岩浅大神经切断术在难治性鼻炎的手术治疗中确实有作用,特别是在非过敏性鼻炎患者中,但设计良好的队列试验将有助于阐明长期结局。

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