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克什米尔人群中希腊和犹太血统混合的全基因组搜索。

A Genome-Wide Search for Greek and Jewish Admixture in the Kashmiri Population.

作者信息

Downie Jonathan M, Tashi Tsewang, Lorenzo Felipe Ramos, Feusier Julie Ellen, Mir Hyder, Prchal Josef T, Jorde Lynn B, Koul Parvaiz A

机构信息

Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

出版信息

PLoS One. 2016 Aug 4;11(8):e0160614. doi: 10.1371/journal.pone.0160614. eCollection 2016.

Abstract

The Kashmiri population is an ethno-linguistic group that resides in the Kashmir Valley in northern India. A longstanding hypothesis is that this population derives ancestry from Jewish and/or Greek sources. There is historical and archaeological evidence of ancient Greek presence in India and Kashmir. Further, some historical accounts suggest ancient Hebrew ancestry as well. To date, it has not been determined whether signatures of Greek or Jewish admixture can be detected in the Kashmiri population. Using genome-wide genotyping and admixture detection methods, we determined there are no significant or substantial signs of Greek or Jewish admixture in modern-day Kashmiris. The ancestry of Kashmiri Tibetans was also determined, which showed signs of admixture with populations from northern India and west Eurasia. These results contribute to our understanding of the existing population structure in northern India and its surrounding geographical areas.

摘要

克什米尔人群是一个居住在印度北部克什米尔山谷的民族语言群体。一个长期存在的假设是,这个群体的祖先来自犹太和/或希腊血统。有古希腊人在印度和克什米尔存在的历史和考古证据。此外,一些历史记载也表明有古代希伯来血统。迄今为止,尚未确定在克什米尔人群中是否能检测到希腊或犹太混合血统的特征。通过全基因组基因分型和混合血统检测方法,我们确定现代克什米尔人中没有希腊或犹太混合血统的显著或大量特征。克什米尔藏族人的祖先也已确定,显示出与印度北部和西欧亚人群混合的迹象。这些结果有助于我们了解印度北部及其周边地理区域现有的人口结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a3/4973929/b4f4fbcb858c/pone.0160614.g001.jpg

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