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影像学诊断——犬脊髓和脑部多灶性少突胶质细胞瘤的磁共振成像特征

IMAGING DIAGNOSIS-MAGNETIC RESONANCE IMAGING FEATURES OF A MULTIFOCAL OLIGODENDROGLIOMA IN THE SPINAL CORD AND BRAIN OF A DOG.

作者信息

Schkeeper Amy E, Moon Rachel, Shrader Stephanie, Koehler Jey W, Linden Daniel, Taylor Amanda R

机构信息

Department of Clinical Sciences, Auburn University College of Veterinary Medicine, 5540 Wire Road, Auburn, AL, 36849.

Department of Pathobiology, Auburn University College of Veterinary Medicine, 5540 Wire Road, Auburn, AL, 36849.

出版信息

Vet Radiol Ultrasound. 2017 Sep;58(5):E49-E54. doi: 10.1111/vru.12401. Epub 2016 Aug 4.

Abstract

An 8-year-old neutered male Toy Poodle was presented with chronic, progressive tetraparesis, and possible seizures. Magnetic resonance images demonstrated an extensive, T1 and T2 hyperintense contrast enhancing mass in the cervical spinal cord. Three nodules were present on the surface of the thalamus, with enhancement most evident on delayed images. A diagnosis of high-grade oligodendroglioma was confirmed with postmortem histopathology and immunohistochemical labeling. Oligodendroglioma should be considered as a differential for T1 hyperintense intraaxial or intramedullary lesions with contrast enhancement. If enhancement is not visualized on postcontrast images, delayed images may be beneficial.

摘要

一只8岁已绝育的雄性玩具贵宾犬出现慢性进行性四肢轻瘫,并可能伴有癫痫发作。磁共振成像显示颈髓有一个广泛的、T1和T2高信号且有对比增强的肿块。丘脑表面有三个结节,延迟图像上强化最为明显。死后组织病理学和免疫组织化学标记证实为高级别少突胶质细胞瘤。少突胶质细胞瘤应被视为T1高信号轴内或髓内病变且有对比增强的鉴别诊断之一。如果在增强后图像上未观察到强化,延迟图像可能会有所帮助。

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