Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Dushu Lake Campus, Soochow University , Suzhou, 215123, People's Republic of China.
J Org Chem. 2016 Sep 2;81(17):8070-6. doi: 10.1021/acs.joc.6b01466. Epub 2016 Aug 15.
The first utility of praseodymium as a mediating metal in the Barbier reaction of carbonyl compounds with allyl halides was reported in this paper. In contrast to the traditional metal-mediated or catalyzed Barbier reactions, exclusive α-adducts were obtained in this one-pot reaction with a broad scope of substrates and feasible reaction conditions.
本文报道了镨作为介导金属在羰基化合物与烯丙基卤化物的 Barbiere 反应中的首次应用。与传统的金属介导或催化的 Barbiere 反应相比，在这种一锅反应中，使用广泛的底物和可行的反应条件，可以得到独特的α-加合物。
