Dejonckheere M, Barvais L
Rev Med Brux. 1989 Apr;10(4):148-53.
With the first autotransfusion systems blood was aspirated by the surgeon, anticoagulated and immediately reinfused to the patient. Modern devices convert salvaged blood to a concentrated red cell solution almost devoid of anticoagulant and free hemoglobin. Autotransfusion reduces blood bank requirements in aortic, cardiac and orthopedic surgery; however septic and/or neoplastic contamination of the surgical field precludes the use of this technique. Massive autotransfusion may induce dilution of platelets and coagulation factors sometimes responsible of coagulopathy. Widespread use of autotransfusion is still limited not only by the cost of the devices but also by the need for trained staff to operate the system.
在第一代自体输血系统中,外科医生抽吸血液,进行抗凝处理后立即回输给患者。现代设备可将回收的血液转化为几乎不含抗凝剂和游离血红蛋白的浓缩红细胞溶液。自体输血可减少主动脉、心脏和骨科手术中的血库需求;然而,手术区域的感染和/或肿瘤污染排除了该技术的使用。大量自体输血可能会导致血小板和凝血因子稀释,有时会引发凝血病。自体输血的广泛应用仍然受到限制,不仅因为设备成本,还因为需要训练有素的工作人员来操作该系统。