Jerin C, Krause E, Ertl-Wagner B, Gürkov R
Deutsches Schwindel- und Gleichgewichtszentrum, Klinikum der Universität München, Marchioninistr. 15, 81377, München, Deutschland.
Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Klinikum der Universität München, München, Deutschland.
HNO. 2016 Dec;64(12):911-916. doi: 10.1007/s00106-016-0198-7.
The aim of this study was to compare the clinical history and the findings in audiovestibular function tests in patients suffering from intralabyrinthine schwannoma or delayed endolymphatic hydrops (DEH).
Five patients diagnosed with intralabyrinthine schwannoma by magnetic resonance imaging (MRI) and five patients diagnosed with DEH by locally enhanced inner ear MRI (LEIM) were retrospectively studied.
All patients with intralabyrinthine schwannoma or DEH initially presented with hearing loss. Vertigo occurred in two patients with intralabyrinthine schwannoma and in all patients with DEH. While audiometry achieved poorer results for patients with intralabyrinthine schwannomas, vestibular function tests revealed normal results in about half of the patients in both groups.
Patients with intralabyrinthine schwannomas may present with clinical symptoms similar to patients suffering from other inner ear disorders like delayed endolymphatic hydrops and may obtain similar findings in audiovestibular function tests. High-resolution MR imaging with locally applied contrast agent may provide evidence of both underlying pathologies.
本研究旨在比较患迷路内神经鞘瘤或迟发性内淋巴积水(DEH)患者的临床病史及听前庭功能测试结果。
回顾性研究5例经磁共振成像(MRI)诊断为迷路内神经鞘瘤的患者以及5例经局部增强内耳MRI(LEIM)诊断为DEH的患者。
所有迷路内神经鞘瘤或DEH患者最初均表现为听力损失。2例迷路内神经鞘瘤患者及所有DEH患者出现眩晕。虽然听力测定显示迷路内神经鞘瘤患者结果较差,但前庭功能测试显示两组约半数患者结果正常。
迷路内神经鞘瘤患者可能出现与迟发性内淋巴积水等其他内耳疾病患者相似的临床症状,且在听前庭功能测试中可能获得相似结果。局部应用造影剂的高分辨率磁共振成像可能为两种潜在病变提供证据。