Repaske David R
Department of Pediatrics, University of Virginia, Charlottesville.
Pediatr Diabetes. 2016 Sep;17(6):392-7. doi: 10.1111/pedi.12406.
Epidemiological studies and case reports have demonstrated an increased rate of development of diabetes mellitus consequent to taking diverse types of medication. This review explores this evidence linking these medications and development of diabetes and presents postulated mechanisms by which the medications might cause diabetes. Some medications are associated with a reduction in insulin production, some with reduction in insulin sensitivity, and some appear to be associated with both reduction in insulin production and insulin sensitivity.
流行病学研究和病例报告表明,服用多种药物后糖尿病的发病率有所上升。本综述探讨了将这些药物与糖尿病发病联系起来的证据,并提出了这些药物可能导致糖尿病的假定机制。一些药物与胰岛素分泌减少有关,一些与胰岛素敏感性降低有关,还有一些似乎与胰岛素分泌和胰岛素敏感性降低都有关。