Archambeaud-Mouveroux F, Dejax C, DeBuhan B, Bonnaud F
Department of Internal Medicine, Hospital Le Cluzeau, Limoges, France.
South Med J. 1989 Jul;82(7):907-10. doi: 10.1097/00007611-198907000-00028.
We have reported a case of toxic thyroid adenoma with low T3 and low T4 syndrome in a patient who received antituberculous drugs for active pulmonary tuberculosis. Search for thyroid-hormone-binding antibodies was negative. Thyroid lobectomy was done and histologic examination confirmed toxic thyroid adenoma; two months after operation the patient was clinically and biologically euthyroid. During the course of a severe nonthyroidal illness, normal thyroid hormone levels must be regarded as an indicator of hyperthyroidism. In addition, we believe that rifampin has a significant effect on thyroid function tests and results of thyroid physiology.
我们报告了一例患有低T3和低T4综合征的毒性甲状腺腺瘤患者，该患者因活动性肺结核正在接受抗结核药物治疗。甲状腺激素结合抗体检测为阴性。实施了甲状腺叶切除术，组织学检查证实为毒性甲状腺腺瘤；术后两个月患者在临床和生物学上均处于甲状腺功能正常状态。在严重的非甲状腺疾病过程中，正常的甲状腺激素水平必须被视为甲状腺功能亢进的一个指标。此外，我们认为利福平对甲状腺功能测试及甲状腺生理学结果有显著影响。
