在小儿磁共振小肠造影中，融合扩散加权成像（DWI）/T2图像与对比增强图像检测肠道炎症并与组织病理学进行相关性分析。
Detection of bowel inflammation with fused DWI/T2 images versus contrast-enhanced images in pediatric MR enterography with histopathologic correlation.
作者信息
Ehman Eric C, Phelps Andrew S, Ohliger Michael A, Rhee Sue J, MacKenzie John D, Courtier Jesse L
机构信息
Department of Radiology and Biomedical Imaging, UCSF, 505 Parnassus Ave., San Francisco, CA 94143-0628.
Department of Radiology and Biomedical Imaging, UCSF Benioff Children's Hospital, 1975 4th Street, CL1578L, San Francisco, CA 94158.
出版信息
Clin Imaging. 2016 Nov-Dec;40(6):1135-1139. doi: 10.1016/j.clinimag.2016.07.006. Epub 2016 Jul 21.
PURPOSE
To evaluate the fused, colorized diffusion weighted imaging (DWI) and anatomic T2 images compared to routine contrast-enhanced T1 images at pediatric magnetic resonance enterography (MRE).
METHODS
Fused, colorized DWI/T2 images were created from patients with magnetic resonance enterography (MRE) and colonoscopy/biopsy. Radiologists noted inflammation in five bowel segments (terminal ileum-rectosigmoid colon) on postcontrast images and DWI/T2 images. Test characteristics and agreement were calculated.
RESULTS
For 20 patients, sensitivity/specificity/positive predictive value (PPV)/negative predictive value (NPV) were 0.53/0.90/0.77/0.76 for DWI/T2 and 0.45/0.90/0.72/0.73 for postcontrast images. Intraobserver agreement was ҡ=0.45-0.73. Interobserver agreement was ҡ=0.53 for DWI/T2 and ҡ=0.63 for postcontrast images.
CONCLUSION
DWI/T2 images are similar in sensitivity/specificity to contrast-enhanced images and with moderate intra/interobserver reliability.
目的
在儿童磁共振小肠造影（MRE）中，评估融合的、彩色的扩散加权成像（DWI）与解剖T2图像，并与常规对比增强T1图像进行比较。
方法
从接受磁共振小肠造影（MRE）以及结肠镜检查/活检的患者中生成融合的、彩色的DWI/T2图像。放射科医生在对比增强图像和DWI/T2图像上记录五个肠段（回肠末端 - 直肠乙状结肠）的炎症情况。计算检测特征和一致性。
结果
对于20名患者，DWI/T2的敏感性/特异性/阳性预测值（PPV）/阴性预测值（NPV）分别为0.53/0.90/0.77/0.76，对比增强图像的分别为0.45/0.90/0.72/0.73。观察者内一致性系数κ=0.45 - 0.73。DWI/T2的观察者间一致性系数κ=0.53，对比增强图像的观察者间一致性系数κ=0.63。
结论
DWI/T2图像在敏感性/特异性方面与对比增强图像相似，且观察者内/间可靠性中等。
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