Llewellyn L E, Endean R
School of Biochemistry, University of New South Wales, Kensington, Australia.
Toxicon. 1989;27(5):596-600. doi: 10.1016/0041-0101(89)90122-0.
Purification of toxic aqueous extracts from the xanthid crabs Zosimus aeneus and Lophozozymus pictor, collected from Australian waters, yielded paralytic shelfish toxins, including saxitoxin (STX), neosaxitoxin (neoSTX) and gonyautoxins 1, 2 and 4 (GTX1,2,4). No more than two paralytic shellfish toxins were found in any of the purified extracts from any specimen. Four specimens of Z. aeneus and one specimen of L. pictor each contained more toxic material than the suggested human oral lethal dose. The moult of a specimen of L. pictor was toxic, which may indicate a route in crabs for toxin removal.
从澳大利亚海域采集的扇蟹科动物铜铸熟若蟹和斑纹爱洁蟹的有毒水提物经纯化后,得到了麻痹性贝类毒素,包括石房蛤毒素(STX)、新石房蛤毒素(neoSTX)以及膝沟藻毒素1、2和4(GTX1、2、4)。在任何一个标本的纯化提取物中,发现的麻痹性贝类毒素均不超过两种。四只铜铸熟若蟹标本和一只斑纹爱洁蟹标本所含的有毒物质均超过了建议的人类口服致死剂量。一只斑纹爱洁蟹标本的蜕壳具有毒性,这可能表明蟹类存在毒素清除途径。