Katsuta Osamu, Shibata Toru, Kuriki-Yamamoto Yumi, Mochizuki Takaharu, Yoshimi Miwa, Noto Takahisa, Mano Hidetoshi
Toxicology and Pharmacokinetics Group, Non-clinical Research, R&D Division, Santen Pharmaceutical Co., Ltd., 8916-16 Takayama-cho, Ikoma-shi, Nara 630-0101, Japan.
J Vet Med Sci. 2016 Dec 1;78(11):1741-1743. doi: 10.1292/jvms.16-0286. Epub 2016 Aug 6.
A 15-year-old male cynomolgus monkey (Macaca fascicularis) showed large bilateral masses in the maxillary sinus. In histopathological examination, both masses revealed benign medullary lipomas within the turbinate bones. The tumors were composed of well-developed lipocytes, trabecular bones and a few blood vessels. Although we initially diagnosed the tumor as bilateral lipomas in the nasal turbinates, it was not differentiated from lipomatous hamartoma. Findings, such as unique symmetrical proliferation, lack of border from the normal marrow and the intact surrounding tissue, indicated a lipomatous hamartoma/hamartomatous lipoma, thought to be a suitable diagnosis of the lesion. Of most interest was that such a proliferating lesion occurred in the nasal turbinate.
一只15岁的雄性食蟹猴(猕猴)上颌窦出现双侧巨大肿块。组织病理学检查显示,两个肿块均为鼻甲内的良性髓脂肪瘤。肿瘤由发育良好的脂肪细胞、小梁骨和少量血管组成。尽管我们最初将肿瘤诊断为双侧鼻甲脂肪瘤,但它与脂肪瘤性错构瘤并无区别。独特的对称性增生、与正常骨髓无边界以及周围组织完整等表现提示为脂肪瘤性错构瘤/错构瘤性脂肪瘤,这被认为是对该病变的合适诊断。最令人感兴趣的是,这样一个增生性病变发生在鼻甲。