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[大鼠大脑皮层的温度反应及实验诱发兴奋灶的远距离效应]

[Temperature reactions of the cerebral cortex in the rat and the distant effect of an experimentally evoked excitatory focus].

作者信息

Rusinov V S, Tsykalov E N, Kuznetsova G D

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Mar-Apr;39(2):320-8.

PMID:2750294
Abstract

By means of dynamic thermovision method, distant reactions of the cerebral cortex were studied in white rats appearing under local chemical action (2% KCl). Besides the previously described temperature wave SD (T-wave), in these conditions in the contralateral hemisphere local areas of warming up (0.2-0.3 degrees) were observed symmetrical with the place of stimulation. Under local chemical action, latent foci of excitation were revealed on dynamic thermal maps of the brain surface in the areas of the same or contralateral hemisphere, distant from the places of stimulation. During creation of two K+ foci a change was observed of place of T-wave appearance and of the usual order of its propagation over the cortex and also the formation of a focus of prolonged temperature fluctuations in the place of two T-waves meeting. On the basis of the obtained data a number of questions is discussed on the forms and mechanisms of distant effects in the CNS.

摘要

通过动态热成像方法,研究了局部化学作用(2%氯化钾)下大白鼠大脑皮层的远距离反应。除了先前描述的温度波SD(T波)外,在这些条件下,对侧半球与刺激部位对称的局部区域出现了升温(0.2 - 0.3度)。在局部化学作用下,在大脑表面动态热图上,在与刺激部位同侧或对侧半球的区域发现了潜在的兴奋灶,这些区域远离刺激部位。在形成两个钾离子灶的过程中,观察到T波出现的位置及其在皮层上通常的传播顺序发生了变化,并且在两个T波相遇的位置形成了一个持续温度波动的焦点。根据所获得的数据,讨论了中枢神经系统中远距离效应的形式和机制等一系列问题。

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