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老年创伤患者中可回收下腔静脉滤器的应用:是否存在年龄偏见?

Retrievable inferior vena cava filters in geriatric trauma: Is there an age bias?

作者信息

Urias Daniel, Silvis Jennifer, Mesropyan Lusine, Oberlander Emma, Simunich Thomas, Tretter James

机构信息

General Surgery Resident Conemaugh Memorial Medical Center, Johnstown, PA, United States.

Research Associate Conemaugh Memorial Medical Center, Johnstown, PA, United States.

出版信息

Injury. 2017 Jan;48(1):148-152. doi: 10.1016/j.injury.2016.07.008. Epub 2016 Jul 15.

Abstract

BACKGROUND

Trauma patients are at increased risk for developing venous thromboembolic (VTE) disease. The EAST (Eastern Association for the Surgery of Trauma) practice management guidelines identified risk factors for VTE, as well as indications for prophylactic inferior vena cava filters (IVCF). In a 2009 study, our institution found a 26% retrieval rate for IVCF. Lack of retrieval was most consistently due to lack of follow-up. Our study is a follow-up analysis for retrieval rate of IVCF, since the formation of a geriatric trauma service. We anticipated that geriatric trauma patients would have a lower rate of IVCF retrieval compared to the general trauma patient.

METHODS

Our study population consisted of trauma patients admitted from January 2008 to August 2013, with documented VTE or high risk for VTE with contraindication to anticoagulation.

INCLUSION CRITERIA

IVCF placed in trauma patients.

EXCLUSION CRITERIA

permanent filters, retrievable filters placed permanently, non-trauma patients, superior vena cava filters and patients who died before discharge.

RESULTS

During the study period, 160 trauma patients had an IVCF placed, of which 147 survived and were discharged. Of those patients, 66% (97/147) were planned for retrieval. Overall, the retrieval rate was 34% (33/97). Following age categorization, rates were 47% (30/64) and 9% (3/33) for those <65 and >/=65 years old, respectively. Applying Fisher's Exact Test to a crosstab of planned retrieval by age category yielded a statistically significant difference, p<0.0005 at alpha=0.05. In the geriatric population with IVCFs not retrieved, 23% (7/30) died and 67% (20/30) were lost to follow-up.

CONCLUSION

IVCF plays a critical role in the management of trauma patients with VTE, particularly the geriatric population. Since our 2009 study, we have improved nearly ten percentage points (26% to 34%); however, we exposed an age bias with retrieval rate being lower in patients >/=65 compared to those <65 (9% vs. 47%).

摘要

背景

创伤患者发生静脉血栓栓塞(VTE)疾病的风险增加。美国东部创伤外科学会(EAST)的实践管理指南确定了VTE的危险因素以及预防性下腔静脉滤器(IVCF)的适应证。在2009年的一项研究中,我们机构发现IVCF的取出率为26%。未取出的最常见原因是缺乏随访。我们的研究是自老年创伤服务形成以来对IVCF取出率的一项随访分析。我们预计老年创伤患者的IVCF取出率低于普通创伤患者。

方法

我们的研究人群包括2008年1月至2013年8月入院的创伤患者,这些患者有记录的VTE或有VTE高风险且有抗凝禁忌证。

纳入标准

在创伤患者中置入IVCF。

排除标准

永久性滤器、永久性置入的可取出滤器、非创伤患者、上腔静脉滤器以及出院前死亡的患者。

结果

在研究期间,160例创伤患者置入了IVCF,其中147例存活并出院。在这些患者中,66%(97/147)计划取出。总体而言,取出率为34%(33/97)。按年龄分类后,年龄<65岁和≥65岁患者的取出率分别为47%(30/64)和9%(3/33)。对按年龄分类的计划取出情况进行交叉表分析并应用Fisher精确检验,结果显示存在统计学显著差异,在α = 0.05时p<0.0005。在未取出IVCF的老年人群中,23%(7/30)死亡,67%(20/30)失访。

结论

IVCF在VTE创伤患者的管理中起着关键作用,尤其是老年人群。自我们2009年的研究以来,我们已将取出率提高了近10个百分点(从26%提高到34%);然而,我们发现了年龄偏差,≥65岁患者的取出率低于<65岁患者(9%对47%)。

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