Stanford University Medical Center, 300 Pasteur Drive, Rm H1330, Stanford, CA, 94305, USA.
Duke University Medical Center, Box 3808 DUMC, Durham, NC, 27710, USA.
Abdom Radiol (NY). 2017 Jan;42(1):90-100. doi: 10.1007/s00261-016-0861-1.
One of the significant challenges facing radiologists who perform and interpret studies of the gastrointestinal and genitourinary systems have been periodic interruptions in the availability of barium and iodinated contrast media specially formulated for gastrointestinal (GI) and genitourinary (GU) studies. These interruptions are due to the US Food and Drug Administration's recent requirement for more stringent documentation of the safety and efficacy of contrast media and the consolidation among contrast manufacturers. Therefore, radiologists may be required to recommend an alternative means of evaluation, such as computed tomography, magnetic resonance, or endoscopy, or they may need to substitute a different formulation of a contrast agent not specifically developed for GI or GU use, for example the utilization of an agent designed and marketed for vascular use. This article reviews the current status of fluoroscopic contrast media, and provides suggestions and recommendations for the optimal and alternative use of contrast media formulations.
从事胃肠道和泌尿生殖系统影像学检查和解释的放射科医生面临的一个重大挑战是，专门用于胃肠道（GI）和泌尿生殖系统（GU）研究的钡和碘对比剂的供应会定期中断。这些中断是由于美国食品和药物管理局最近要求更严格地记录对比剂的安全性和有效性，以及对比剂制造商的整合。因此，放射科医生可能需要建议替代评估方法，例如计算机断层扫描、磁共振成像或内窥镜检查，或者他们可能需要替代一种不是专门为 GI 或 GU 使用开发的对比剂的不同配方，例如使用专为血管使用设计和销售的造影剂。本文回顾了透视对比剂的现状，并为对比剂配方的最佳和替代使用提供了建议和推荐。
