Červená Barbora, Brant Sara Vanessa, Fairet Emilie, Shirley Matthew H, Petrželková Klára Judita, Modrý David
University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.
University of New Mexico, Albuquerque, New Mexico.
Am J Trop Med Hyg. 2016 Oct 5;95(4):849-851. doi: 10.4269/ajtmh.16-0446. Epub 2016 Aug 8.
Schistosomiasis affects millions of people across Africa. We detected eggs of Schistosoma mansoni in western lowland gorilla and central chimpanzee fecal samples in Loango National Park, Gabon. We analyzed nuclear and mitochondrial DNA, namely internal transcribed spacer and cytochrome c oxidase subunit 1 fragments, and the resulting maximum likelihood phylogenetic analyses and haplotype network of the ITS and COI, respectively, showed that the samples from gorillas and chimpanzees clustered clearly within the S. mansoni clade. This is the first confirmed record of S. mansoni from Gabon, which urges surveillance in the area and prompts questions regarding the extent of zoonotic transmission and the clinical impact.
血吸虫病影响着非洲数百万人。我们在加蓬卢安果国家公园的西部低地大猩猩和黑猩猩粪便样本中检测到了曼氏血吸虫卵。我们分析了核DNA和线粒体DNA,即内转录间隔区和细胞色素c氧化酶亚基1片段,对ITS和COI分别进行的最大似然系统发育分析和单倍型网络分析表明,来自大猩猩和黑猩猩的样本明显聚集在曼氏血吸虫分支内。这是加蓬首次确认的曼氏血吸虫记录,这促使对该地区进行监测,并引发了关于人畜共患病传播范围和临床影响的问题。