Eom Hye-Joung, Yang Dong Hyun, Kim Young-Hak, Roh Jae-Hyung, Kweon Jihoon, Kang Soo-Jin, Kim Namkug, Kang Joon-Won, Lim Tae-Hwan
Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olimpic-ro 43 gil, Songpa-gu, 05505, Seoul, South Korea.
Department of Cardiology and Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Int J Cardiovasc Imaging. 2016 Nov;32(11):1659-1665. doi: 10.1007/s10554-016-0953-6. Epub 2016 Aug 9.
The aim of this study is to analyze post-bifurcation coronary stent morphology in vitro using dual-source CT and validate those findings using micro-CT. Nine silicon coronary artery phantoms simulating main branch (MB) and side branch (SB) were prepared using a 3-D printer. After bifurcation stenting using Crush, Culotte, and T-stenting technique, in vitro CT imaging was conducted using both dual-source CT and micro-CT. Morphological change of the bifurcation stent including crushed segment and floating stent strut were evaluated. Dual-source CT was able to demonstrate morphologic changes of bifurcation stents and was comparable to micro-CT. In stents with Crush and T-stenting methods, crushed segment appeared denser and thicker than other stent parts and was located at MB side in all phantoms. Floating strut was observed in half of the phantoms with Crush technique and all phantoms with T-stenting. Parameters measured in both dual-source CT and micro-CT showed good correlation and high agreement (limits of agreement and correlation for length, perimeter and area, 0.3 ± 3.5, 0.5 ± 2.1 mm, and 0.0 ± 1.5 mm², r = 0.76, 0.92, and 0.91). The morphology of post-bifurcation stent on dual-source CT correlates well with that of micro-CT in the coronary artery phantom. Coronary CT angiography may be a feasible method for the evaluation of stent morphology in patients who underwent bifurcation stenting.
本研究的目的是使用双源CT在体外分析分叉后冠状动脉支架的形态,并使用微CT验证这些发现。使用3D打印机制作了九个模拟主支(MB)和边支(SB)的硅质冠状动脉模型。在使用挤压术、裤裙式支架术和T型支架术进行分叉支架置入术后,使用双源CT和微CT进行体外CT成像。评估分叉支架的形态变化,包括受压段和漂浮支架支柱。双源CT能够显示分叉支架的形态变化,并且与微CT相当。在采用挤压术和T型支架术的支架中,受压段比其他支架部分显得更致密、更厚,并且在所有模型中均位于主支一侧。在一半采用挤压术的模型和所有采用T型支架术的模型中观察到了漂浮支柱。在双源CT和微CT中测量的参数显示出良好的相关性和高度一致性(长度、周长和面积的一致性界限和相关性分别为0.3±3.5、0.5±2.1mm和0.0±1.5mm²,r = 0.76、0.92和0.91)。在冠状动脉模型中,双源CT上分叉后支架的形态与微CT的形态具有良好的相关性。冠状动脉CT血管造影可能是评估接受分叉支架置入术患者支架形态的一种可行方法。