Islam Farrah
Al-Shifa Trust Eye Hospital, Rawalpindi.
J Coll Physicians Surg Pak. 2016 Jul;26(7):598-601.
To determine the relationship between foveal (retinal) thickness and visual acuity in diabetic macular edema through optical coherence tomography (OCT) mapping software.
Cross-sectional descriptive study.
The Retina Clinic of Al-Shifa Trust Eye Hospital, Rawalpindi, from August 2011 to August 2012.
Eighty eyes of 68 patients with clinical diagnosis of diabetic macular edema, based on complete ophthalmic examination, were enrolled. The best-corrected visual acuity was recorded on logMar scale. OCTimaging was performed through dilated pupil by experienced operator. Foveal thickness was determined. OCTparameters of macular thickness were analysed with baseline variables including age, duration since diagnosed with diabetes, and visual acuity.
The mean visual acuity was 0.81 (0.2 - 1.8) logMar units. The average foveal thickness was 395.09 ±142.26 (183 - 825 µm). There was moderate correlation between foveal thickness and visual acuity (rs= 0.574, p < 0.001), absent in those who had visual acuity worse than 1 logMar. There was a weak positive association between foveal thickness and the duration of diabetes (rs=0.249, p < 0.05). There was, however, no correlation between foveal thickness and age (rs= 0.012, p=0.919).
There is a moderate correlation between visual acuity and degree of foveal thickening in diabetic macular edema, hence two cannot be used interchangeably in clinical practice.
通过光学相干断层扫描（OCT）测绘软件确定糖尿病性黄斑水肿患者的黄斑（视网膜）厚度与视力之间的关系。
横断面描述性研究。
2011年8月至2012年8月，拉瓦尔品第阿法信托眼科医院视网膜诊所。
纳入68例经全面眼科检查临床诊断为糖尿病性黄斑水肿患者的80只眼。采用对数最小分辨角（logMar）视力表记录最佳矫正视力。由经验丰富的操作人员通过散瞳进行OCT成像，测定黄斑厚度。分析黄斑厚度的OCT参数与包括年龄、糖尿病确诊时间和视力在内的基线变量之间的关系。
平均视力为0.81（0.2 - 1.8）logMar单位。平均黄斑厚度为395.09±142.26（183 - 825µm）。黄斑厚度与视力之间存在中度相关性（rs = 0.574，p < 0.001），视力差于1 logMar的患者不存在这种相关性。黄斑厚度与糖尿病病程之间存在弱正相关（rs = 0.249，p < 0.05）。然而，黄斑厚度与年龄之间无相关性（rs = 0.012，p = 0.919）。
糖尿病性黄斑水肿患者的视力与黄斑增厚程度之间存在中度相关性，因此在临床实践中二者不能相互替代。
