FULL-THICKNESS MACULAR HOLE COMBINED WITH PIGMENT EPITHELIAL DETACHMENT USING MULTIMODAL IMAGING.
作者信息
Inoue Maiko, Tan Anna, Slakter Jason S, Chang Stanley, Kadonosono Kazuaki, Yannuzzi Lawrence A
机构信息
*Vitreous Retina Macula Consultants of New York, New York, New York; †The LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, New York, New York; ‡Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan; §Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore; and ¶Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York.
出版信息
Retin Cases Brief Rep. 2017;11(4):369-372. doi: 10.1097/ICB.0000000000000373.
PURPOSE
To describe two patients who showed full-thickness macular holes (FTMH) combined with pigment epithelial detachments (PED) and had contrasting outcomes to treatment.
METHODS
A retrospective report of two cases.
RESULTS
Case 1 was treated with intravitreal antivascular endothelial growth factor and photodynamic therapy, and the PED flattened. Subsequently, a vitrectomy was performed and the FTMH closed. Her visual acuity improved from 20/200 to 20/25. In Case 2, the same medical therapy, with less frequency compared with Case 1, did not affect the PED, and the FTMH failed to close with surgery. Later, a spontaneous collapse of the PED occurred but the FTMH was persistent with an associated poor visual acuity of 20/200.
CONCLUSION
Full-thickness macular hole is rare, but can occur in association with large PEDs. Although the pathologic mechanism was uncertain, visual outcomes were dependent on response to treatments of the PED, as well as anatomical closure of the FTMH.
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