急性自主神经和感觉神经病：一例尸检病例报告。

Acute autonomic and sensory neuropathy: report of an autopsy case.

作者信息

Tohgi H, Sano M, Sasaki K, Suzuki H, Sato T, Iwasaki T, Satodate R

机构信息

Department of Neurology, Iwate Medical University, Japan.

出版信息

Acta Neuropathol. 1989;77(6):659-63. doi: 10.1007/BF00687895.

DOI:10.1007/BF00687895

PMID:2750481

Abstract

A 46-year-old woman presented acute sensorimotor neuropathy of the Guillain-Barré type, followed by a protracted course of profound autonomic and sensory dysfunction. Tests of autonomic functions showed denervation hypersensitivity. Neuropathologically, the trigeminal sensory nuclei, solitary nucleus, the dorsal columns of the spinal cord and dorsal spinal roots showed severe degeneration. Degeneration was found both in the preganglionic (intermediolateral cell columns of the spinal cord) and postganglionic (sympathetic ganglion and celiac ganglion) neurons of the sympathetic nervous system, and the preganglionic (dorsal motor nucleus of the vagus) and postganglionic (Auerbach's plexus) neurons of the parasympathetic nervous system.

摘要

一名46岁女性出现吉兰-巴雷型急性感觉运动神经病，随后是长期严重的自主神经和感觉功能障碍。自主神经功能测试显示失神经超敏反应。神经病理学检查发现，三叉神经感觉核、孤束核、脊髓后索和脊髓后根严重变性。交感神经系统的节前神经元（脊髓中间外侧细胞柱）和节后神经元（交感神经节和腹腔神经节）以及副交感神经系统的节前神经元（迷走神经背运动核）和节后神经元（奥尔巴赫神经丛）均有变性。