Hawkins Alexander T, Dharmarajan Sekhar, Wells Katerina K, Krishnamurty Devi Mukkai, Mutch Matthew G, Glasgow Sean C
Department of Surgery, Section of Colon and Rectal Surgery, Washington University in St. Louis, 660 S. Euclid Avenue, St. Louis, MO, 63110, USA.
J Gastrointest Surg. 2016 Oct;20(10):1738-43. doi: 10.1007/s11605-016-3230-z. Epub 2016 Aug 9.
Anastomotic leak is one of the most feared complications of gastrointestinal surgery. Surgeons routinely perform a diverting loop ileostomy (DLI) to protect high-risk colo-rectal anastomoses.
The NSQIP database was queried from 2012 to 2013 for patients undergoing open ileo-colic resection with and without a DLI. The primary outcome was the development of any anastomotic leak-including those managed operatively and non-operatively. Secondary outcomes included overall complication rate, return to the OR, readmission, and 30-day mortality.
Four thousand one hundred fifty-nine patients underwent open ileo-colic resection during the study period. One hundred eighty-six (4.5 %) underwent a DLI. Factors associated with the addition of a DLI included emergency surgery, pre-operative sepsis, and IBD. There were 197 anastomotic leaks (4.7 %) with 100 patients requiring reoperation (2.4 %). DLI was associated with a decrease in anastomotic leaks requiring reoperation (DLI vs no DLI: 0 (0 %) vs 100 (2.5 %); p = 0.02) and with increased readmission (OR 1.93; 95 % CI 1.30-2.85; p = 0.001).
DLI is rarely used for open ileo-colic resection. There were no serious leaks requiring reoperation in the DLI group. A DLI was associated with an almost two-fold increase in the odds of readmission. Surgeons must weigh the reduction in serious leak rate with postoperative morbidity when considering a DLI for open ileo-colic resection.
吻合口漏是胃肠手术中最令人担忧的并发症之一。外科医生通常会进行转流性回肠造口术(DLI)以保护高危结直肠吻合口。
查询2012年至2013年NSQIP数据库中接受或未接受DLI的开放性回结肠切除术患者。主要结局是发生任何吻合口漏,包括手术处理和非手术处理的情况。次要结局包括总体并发症发生率、返回手术室、再次入院和30天死亡率。
在研究期间,4159例患者接受了开放性回结肠切除术。186例(4.5%)接受了DLI。与增加DLI相关的因素包括急诊手术、术前脓毒症和炎症性肠病。有197例吻合口漏(4.7%),100例患者需要再次手术(2.4%)。DLI与需要再次手术的吻合口漏减少相关(DLI组与非DLI组:0(0%)对100(2.5%);p = 0.02),且与再次入院增加相关(OR 1.93;95%CI 1.30 - 2.85;p = 0.001)。
DLI很少用于开放性回结肠切除术。DLI组没有需要再次手术的严重漏口。DLI与再次入院几率几乎增加两倍相关。在考虑对开放性回结肠切除术使用DLI时,外科医生必须权衡严重漏口率的降低与术后发病率。