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造口术后因脱水导致的再入院:重新思考危险因素。

Readmissions With Dehydration After Ileostomy Creation: Rethinking Risk Factors.

机构信息

Department of Surgery, University of Rochester Medical Center, Rochester, New York.

出版信息

Dis Colon Rectum. 2018 Nov;61(11):1297-1305. doi: 10.1097/DCR.0000000000001137.

Abstract

BACKGROUND

Twenty-nine percent of postileostomy discharges are readmitted, most commonly because of dehydration. However, there is a lack of detailed data specifically evaluating factors associated with readmission with dehydration. In addition, patients with a history of an ileostomy have often been excluded from previous studies and therefore represent a group of understudied ileostomates.

OBJECTIVE

This study aimed to evaluate factors available at discharge associated with 30-day readmission for dehydration, rather than all-cause readmissions.

DESIGN

This was a retrospective cohort study.

SETTING

Study patients received ileostomies at a tertiary academic medical center from 2014 to 2016.

PATIENTS

Patients with a preexisting ileostomy that was not recreated per the operative note were excluded, whereas those who received a new ileostomy were included.

MAIN OUTCOME MEASURE

The primary outcome measured was 30-day readmission for dehydration as defined by objective clinical criteria.

RESULTS

A total of 262 patients underwent ileostomy creation and were discharged alive. Twenty-five percent were ≥65 years of age, 53% were men, 14% had a history of ileostomy, 18% had a creatinine >1.0 on discharge, and 26% had high ileostomy output at any time during the index admission. Among all ileostomates, the all-cause readmission rate was 30%. Mean days to readmission for any cause was 8.5, whereas for dehydration it was 11.6 days. Of the readmissions, 37% were readmitted with a diagnosis of dehydration, and dehydration was the sole reason in 26%. Among those with dehydration, the most common length of stay was 2 days. In multivariable logistic regression, 30-day readmission with dehydration was associated with older age, male sex, history of an ileostomy, high ileostomy output during index admission, and a discharge creatinine >1.0.

LIMITATIONS

This study was limited by its retrospective design.

CONCLUSIONS

Ileostomy dehydration efforts have focused on new ileostomy patients; however, our data suggest that patients with a history of an ileostomy are actually at risk for readmission with dehydration. Further studies aimed at the reduction of readmission with dehydration after ileostomy are warranted and should include patients with a history of an ileostomy. See Video Abstract at http://links.lww.com/DCR/A643.

摘要

背景

29%的回肠造口术后出院患者需要再次入院,最常见的原因是脱水。然而,目前缺乏专门评估与脱水相关的再入院因素的详细数据。此外,既往有回肠造口术病史的患者往往被排除在之前的研究之外,因此他们是一组研究不足的回肠造口术患者。

目的

本研究旨在评估与术后 30 天因脱水而再次入院相关的出院时可获得的因素,而不是所有原因的再入院。

设计

这是一项回顾性队列研究。

地点

研究对象在 2014 年至 2016 年期间在一家三级学术医疗中心接受了回肠造口术。

患者

排除了手术记录中未重建的预先存在的回肠造口术患者,而接受了新回肠造口术的患者则被纳入。

主要观察指标

主要结局指标是根据客观临床标准定义的术后 30 天因脱水而再次入院。

结果

共有 262 例患者接受了回肠造口术并存活出院。25%的患者年龄≥65 岁,53%为男性,14%有回肠造口术病史,18%出院时肌酐>1.0,26%在指数住院期间任何时候回肠造口术的输出量较高。所有回肠造口术患者的全因再入院率为 30%。任何原因的再入院平均天数为 8.5 天,而因脱水的再入院平均天数为 11.6 天。在再入院患者中,37%的患者被诊断为脱水,26%的患者仅因脱水而再次入院。在因脱水而再次入院的患者中,最常见的住院时间为 2 天。多变量逻辑回归分析显示,30 天因脱水而再次入院与年龄较大、男性、有回肠造口术病史、指数住院期间回肠造口术输出量较高以及出院时肌酐>1.0 有关。

局限性

本研究受限于其回顾性设计。

结论

回肠造口术脱水工作主要集中在新的回肠造口术患者上;然而,我们的数据表明,有回肠造口术病史的患者实际上有再次因脱水而入院的风险。需要进一步开展旨在降低回肠造口术后因脱水而再次入院的研究,并且应该包括有回肠造口术病史的患者。

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