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脱水是回肠造口改道术后再入院的最常见指征。

Dehydration is the most common indication for readmission after diverting ileostomy creation.

机构信息

Division of Colon and Rectal Surgery, Penn State Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA.

出版信息

Dis Colon Rectum. 2012 Feb;55(2):175-80. doi: 10.1097/DCR.0b013e31823d0ec5.

Abstract

BACKGROUND

Early readmission after discharge from the hospital is an undesirable outcome. Ileostomies are commonly used to prevent symptomatic anastomotic complications in colorectal resections.

OBJECTIVE

The aim of this study was to identify factors predictive of readmission after colectomy/proctectomy and diverting loop ileostomy.

DESIGN

This study is a retrospective review.

PATIENTS

Patients were included who underwent colon and rectal resections with ileostomy at our institution. Sex, age, type of disease, comorbidities, elective vs urgent procedure, type of ileostomy, operative method, steroid use, ASA score, and the use of diuretics were evaluated as potential factors for readmission.

MAIN OUTCOME MEASURES

The primary outcomes measured were the need for readmission and the presence of dehydration (ostomy output ≥1500 mL over 24 hours and a blood urea nitrogen/creatinine level ≥20, or physical findings of dehydration).

RESULTS

Six hundred three loop ileostomies were created mostly in white (95.3%), male (55.6%) patients undergoing colon or rectal resections. IBD was the most common indication at 50.9%, with rectal cancer at 16.1%, and other at 31.0%. The 60-day readmission rate was 16.9% (n = 102) with the most common cause dehydration (n = 44, 43.1%). Regression analysis demonstrated that the laparoscopic approach (p = 0.02), lack of epidural anesthesia (p = 0.004), preoperative use of steroids (p = 0.04), and postoperative use of diuretics (p = 0.0001) were highly predictive for readmission. Furthermore, regression analysis for readmission for dehydration identified the use of postoperative diuretics as the sole risk factor (p = 0.0001).

LIMITATIONS

This study is limited by the retrospective analysis of data, and it does not capture patients that were treated at home or in clinic.

CONCLUSION

Readmission after colon or rectal resection with diverting loop ileostomy was high at 16.9%. Dehydration was the major cause for readmission. Patients receiving diuretics are at increased risk for readmission for dehydration. High-risk patients should be treated more cautiously as inpatients and closely monitored in the outpatient setting to help reduce dehydration and readmission.

摘要

背景

出院后早期再入院是一种不良结局。回肠造口术常用于预防结直肠切除术后吻合口症状性并发症。

目的

本研究旨在确定与结直肠切除和预防性回肠造口术相关的再入院的预测因素。

设计

这是一项回顾性研究。

患者

本研究纳入在我院行结肠和直肠切除并预防性回肠造口术的患者。评估的潜在因素包括性别、年龄、疾病类型、合并症、择期与紧急手术、回肠造口类型、手术方法、类固醇使用、ASA 评分和利尿剂的使用。

主要观察指标

主要观察指标为再入院的必要性和脱水的发生情况(造口排出量>1500ml/24 小时,血尿素氮/肌酐水平>20 或有脱水的体格检查表现)。

结果

603 例回肠造口术主要在白人(95.3%)、男性(55.6%)患者中实施,用于结肠或直肠切除术。最常见的适应证为炎症性肠病(50.9%),直肠癌(16.1%)和其他疾病(31.0%)。60 天再入院率为 16.9%(n=102),最常见的原因是脱水(n=44,43.1%)。回归分析显示,腹腔镜方法(p=0.02)、无硬膜外麻醉(p=0.004)、术前使用类固醇(p=0.04)和术后使用利尿剂(p=0.0001)与再入院高度相关。此外,针对脱水再入院的回归分析确定术后使用利尿剂是唯一的危险因素(p=0.0001)。

局限性

本研究受数据回顾性分析的限制,未包括在家或在诊所接受治疗的患者。

结论

预防性回肠造口术与结直肠切除术后再入院率高(16.9%)。脱水是再入院的主要原因。使用利尿剂的患者有更高的脱水再入院风险。高危患者应作为住院患者更谨慎地治疗,并在门诊密切监测,以帮助减少脱水和再入院。

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