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内镜超声在肝细胞癌诊断和治疗中的作用。

Role of endoscopic ultrasound in diagnosis and management of hepatocellular carcinoma.

机构信息

Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Department of Gastroenterology and Rheumatology, Fukushima University School of Medicine, Fukushima, Japan.

出版信息

J Hepatocell Carcinoma. 2015 Oct 6;2:143-9. doi: 10.2147/JHC.S60868. eCollection 2015.

DOI:10.2147/JHC.S60868
PMID:27508203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4918294/
Abstract

Hepatocellular carcinoma (HCC) is an aggressive tumor and a leading cause of cancer-related deaths globally. The mortality rate remains high despite many advances in treatment. HCC is frequently diagnosed late in its course due to lack of classical symptoms at earlier stages. Endoscopic ultrasound (EUS) has emerged as an important diagnostic tool for the diagnostic evaluation, staging, and treatment of gastrointestinal tract disorders. EUS-guided fine needle aspiration has been a valuable addition to EUS by being able to obtain tissue under direct visualization. Here, we review the potential role of EUS in the diagnosis and management of HCC. EUS seems to be a safe and reliable alternative method for obtaining tissue for diagnosis of liver cancer, especially for lesions that are inaccessible by traditional methods. EUS could play an important role in the diagnosis and management of HCC.

摘要

肝细胞癌(HCC)是一种侵袭性肿瘤,也是全球癌症相关死亡的主要原因。尽管在治疗方面取得了许多进展,但死亡率仍然很高。由于在早期阶段缺乏典型症状,HCC 常常在病程晚期才被诊断出来。内镜超声(EUS)已成为胃肠道疾病诊断评估、分期和治疗的重要诊断工具。EUS 引导下细针抽吸术通过能够在直接可视化下获取组织,成为 EUS 的一项有价值的补充。在这里,我们回顾了 EUS 在 HCC 的诊断和管理中的潜在作用。EUS 似乎是一种安全可靠的替代方法,可用于获取组织进行肝癌诊断,特别是对于传统方法无法触及的病变。EUS 可以在 HCC 的诊断和管理中发挥重要作用。

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本文引用的文献

1
Endoscopic ultrasound comes of age: Mature, established, creative and here to stay!内镜超声崭露头角:成熟、确立、创新,且行且发展!
Endosc Ultrasound. 2014 Jul;3(3):143-51. doi: 10.4103/2303-9027.138782.
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Endoscopic ultrasound-guided fine needle aspiration: from the past to the future.内镜超声引导下细针抽吸术:从过去到未来。
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Endoscopic ultrasound-guided oncologic therapy for pancreatic cancer.内镜超声引导下胰腺癌的肿瘤治疗
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Cancer statistics, 2013.癌症统计数据,2013 年。
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Endoscopic ultrasound (EUS)-guided ethanol injection for hepatocellular carcinoma difficult to treat with percutaneous local treatment.内镜超声(EUS)引导下乙醇注射治疗经皮局部治疗难以处理的肝细胞癌。
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The global epidemiology of hepatocellular carcinoma: present and future.肝细胞癌的全球流行病学:现状与未来。
Clin Liver Dis. 2011 May;15(2):223-43, vii-x. doi: 10.1016/j.cld.2011.03.006.
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Management of hepatocellular carcinoma: an update.肝细胞癌的管理:最新进展
Hepatology. 2011 Mar;53(3):1020-2. doi: 10.1002/hep.24199.
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Diagnosis of metastatic fibrolamellar hepatocellular carcinoma by endoscopic ultrasound-guided fine needle aspiration.通过内镜超声引导下细针穿刺诊断转移性纤维板层型肝细胞癌
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CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90. doi: 10.3322/caac.20107. Epub 2011 Feb 4.