Soothill P W, Alcock C J, MacKenzie I Z
Department of Obstetrics and Gynaecology, John Radcliffe Maternity Hospital, Oxford.
Br J Obstet Gynaecol. 1989 Apr;96(4):478-81. doi: 10.1111/j.1471-0528.1989.tb02427.x.
Histology reports of endometrial curettage and hysterectomy specimens were compared in patients with stage 1 uterine malignancy. In 63 of 117 (54%) the tumour grade or type reported in the curettage specimen differed from that described in the hysterectomy specimen; the grading was as likely to be more as less well differentiated at hysterectomy. The differences were not related to endometrial sampling technique or pre-operative intracavity radiotherapy. The results suggest that if decisions about patient management continue to be based on histological grading of tumours in endometrial curettage samples, unnecessary morbidity will be caused to some patients and inadequate treatment will be given to others.
对1期子宫恶性肿瘤患者的子宫内膜刮宫标本和子宫切除标本的组织学报告进行了比较。在117例患者中的63例（54%），刮宫标本报告的肿瘤分级或类型与子宫切除标本中描述的不同；子宫切除时分级为高分化和低分化的可能性相同。这些差异与子宫内膜取样技术或术前腔内放疗无关。结果表明，如果继续根据子宫内膜刮宫样本中的肿瘤组织学分级来决定患者的治疗方案，将给一些患者带来不必要的发病率，而另一些患者则得不到充分的治疗。
