Institut de Biologie de l'Ecole Normale Supérieure, Centre National de la Recherche Scientifique (CNRS) UMR8197, Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Ecole Normale Supérieure, 46 rue d'Ulm, 75230 Paris Cedex 05, France.
Institut de Biologie de l'Ecole Normale Supérieure, Centre National de la Recherche Scientifique (CNRS) UMR8197, Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Ecole Normale Supérieure, 46 rue d'Ulm, 75230 Paris Cedex 05, France.
Curr Opin Plant Biol. 2016 Dec;34:27-34. doi: 10.1016/j.pbi.2016.07.010. Epub 2016 Aug 11.
Plants are characterized by a remarkable phenotypic plasticity that meets the constraints of a sessile lifestyle and the need to adjust constantly to the environment. Recent studies have begun to reveal how chromatin dynamics participate in coordinating cell proliferation and differentiation in response to developmental cues as well as environmental fluctuations. In this review, we discuss the pivotal function of chromatin-based mechanisms in cell fate acquisition and maintenance, within as well as outside meristems. In particular, we highlight the emerging role of specific epigenomic factors and chromatin pathways in timing the activity of stem cells, counting cell divisions and positioning cell fate transitions by sensing phytohormone gradients.
植物的表型可塑性非常显著，这使它们能够适应固着生活方式，并不断根据环境进行调整。最近的研究开始揭示染色质动力学如何参与协调细胞增殖和分化，以响应发育线索和环境波动。在这篇综述中，我们讨论了基于染色质的机制在细胞命运获得和维持中的关键作用，包括在分生组织内外。特别是，我们强调了特定的表观遗传因子和染色质途径在通过感知植物激素梯度来定时干细胞活性、计数细胞分裂和定位细胞命运转变方面的新兴作用。
