Theisen Brian K, Wald Abigail I, Singhi Aatur D
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Surg Pathol Clin. 2016 Sep;9(3):441-56. doi: 10.1016/j.path.2016.04.008.
Within the past few decades, there has been a dramatic increase in the detection of incidental pancreatic cysts. It is reported a pancreatic cyst is identified in up to 2.6% of abdominal scans. Many of these cysts, including serous cystadenomas and pseudocysts, are benign and can be monitored clinically. In contrast, mucinous cysts, which include intraductal papillary mucinous neoplasms and mucinous cystic neoplasms, have the potential to progress to pancreatic adenocarcinoma. In this review, we discuss the current management guidelines for pancreatic cysts, their underlying genetics, and the integration of molecular testing in cyst classification and prognostication.
在过去几十年中，偶然发现的胰腺囊肿的检出率急剧上升。据报道，在高达2.6%的腹部扫描中可发现胰腺囊肿。这些囊肿中的许多，包括浆液性囊腺瘤和假性囊肿，都是良性的，可以进行临床监测。相比之下，黏液性囊肿，包括导管内乳头状黏液性肿瘤和黏液性囊性肿瘤，有可能发展为胰腺腺癌。在本综述中，我们讨论了胰腺囊肿的当前管理指南、其潜在遗传学以及分子检测在囊肿分类和预后评估中的整合。
