将分子分析纳入胰腺囊肿的病理评估中。
Integrating Molecular Analysis into the Pathologic Evaluation of Pancreatic Cysts.
机构信息
Department of Pathology, University of Pittsburgh Medical Center, 200 Lothrop St. Pittbsurgh, PA 15213, USA.
Department of Pathology, University of Pittsburgh Medical Center, 200 Lothrop St. Pittbsurgh, PA 15213, USA.
出版信息
Surg Pathol Clin. 2022 Sep;15(3):455-468. doi: 10.1016/j.path.2022.05.009.
The development of cross-sectional imaging techniques has enhanced the detection of pancreatic cystic lesions (PCLs). PCLs are found in approximately 2% of the general population, often as incidentally detected lesions on computed tomography or MRI during the evaluation of other medical conditions. Broadly, PCLs are classified as mucinous or nonmucinous. Mucinous PCLs include mucinous cystic neoplasms and intraductal papillary mucinous neoplasms. Nonmucinous PCLs include pseudocysts, serous cystadenomas, solid pseudopapillary neoplasms, and cystic pancreatic neuroendocrine tumors, as well as cystic acinar cell carcinoma, cystic degeneration of pancreatic ductal adenocarcinoma, lymphoepithelial cyst, and others.
横断面成像技术的发展提高了胰腺囊性病变（PCL）的检出率。PCL 在普通人群中的发现率约为 2%，通常是在评估其他疾病时，通过计算机断层扫描或 MRI 偶然发现的病变。广义上，PCL 分为黏液性和非黏液性。黏液性 PCL 包括黏液性囊腺瘤和导管内乳头状黏液性肿瘤。非黏液性 PCL 包括假性囊肿、浆液性囊腺瘤、实性假乳头状瘤和囊性胰腺神经内分泌肿瘤，以及囊性胰岛细胞瘤、胰腺导管腺癌的囊性变性、淋巴上皮囊肿等。
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