Breakwell Lucy, Vogt Tara M, Fleming Debbie, Ferris Mary, Briere Elizabeth, Cohn Amanda, Liang Jennifer L
Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Epidemic Intelligence Service Program, Division of Scientific Education and Professional Development, Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia.
Office of the Director, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
J Adolesc Health. 2016 Oct;59(4):457-64. doi: 10.1016/j.jadohealth.2016.06.004. Epub 2016 Aug 11.
During March-November 2013, five cases of serogroup B meningococcal disease occurred among University A undergraduates. The Centers for Disease Control and Prevention used the unlicensed MenB-4C (Bexsero, Novartis Vaccines), a serogroup B meningococcal vaccine, to control the outbreak. All undergraduates (n = 19,257) were offered two doses; 51% of undergraduates received ≥1 dose of MenB-4C. We conducted a knowledge, attitudes, and practice survey to understand which factors and sources of information impacted their decision on whether or not to receive vaccine.
An anonymous online survey was sent to University A undergraduates. The survey was implemented in June 2-30, 2014, and covered demographics, MenB-4C vaccination decision, and sources of information. Descriptive analyses were conducted.
A total of 1,341 students completed the survey (response rate = 7.0%), of these 873 received ≥1 dose of MenB-4C. Among vaccinated respondents, the predominant reasons for receiving vaccine were knowledge of disease severity, parental recommendation, and believing that vaccination offered the best protection. Among unvaccinated respondents, the predominant reasons for not receiving vaccine were perception of low disease risk and concern over vaccine newness and safety. Respondents' top primary sources of information were e-mails from the university followed by their parents.
Reasons behind respondents' decision to receive an unlicensed vaccine were similar to those reported for routinely recommended vaccines. Given the challenges around communicating the importance of receiving a vaccine that is not routinely recommended, respondents' primary sources of information, the university and their parents, could be targeted to improve coverage rates.
2013年3月至11月期间，A大学的本科生中发生了5例B群脑膜炎球菌病病例。疾病控制与预防中心使用了未经许可的B群脑膜炎球菌疫苗MenB-4C（Bexsero，诺华疫苗公司）来控制疫情。所有本科生（n = 19,257）都接种了两剂；51%的本科生接种了≥1剂MenB-4C。我们开展了一项知识、态度和行为调查，以了解哪些因素和信息来源影响了他们是否接种疫苗的决定。
向A大学本科生发送了一份匿名在线调查问卷。该调查于2014年6月2日至30日实施，涵盖人口统计学信息、MenB-4C疫苗接种决定以及信息来源。进行了描述性分析。
共有1341名学生完成了调查（回复率 = 7.0%），其中873人接种了≥1剂MenB-4C。在接种疫苗的受访者中，接种疫苗的主要原因是了解疾病的严重性、父母的建议以及认为接种疫苗能提供最佳保护。在未接种疫苗的受访者中，未接种疫苗的主要原因是认为疾病风险低以及担心疫苗的新颖性和安全性。受访者最主要的信息来源是大学发送的电子邮件，其次是他们的父母。
受访者决定接种未经许可疫苗的原因与常规推荐疫苗的情况类似。鉴于在传达接种非常规推荐疫苗的重要性方面存在挑战，可以针对受访者的主要信息来源，即大学和他们的父母，来提高疫苗接种率。
