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家长对脑膜炎 B 型疫苗的认知和为青少年接种疫苗的意愿。

Parental awareness of Meningococcal B vaccines and willingness to vaccinate their teens.

机构信息

Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.

Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA.

出版信息

Vaccine. 2019 Jan 21;37(4):670-676. doi: 10.1016/j.vaccine.2018.11.078. Epub 2018 Dec 23.

Abstract

BACKGROUND

In the US, Meningococcal B (MenB) vaccines were first licensed in 2014. In 2015, the Advisory Committee on Immunization Practices recommended that parents of teens talk to their provider about receiving MenB vaccine, rather than issuing a routine recommendation. We assessed parental awareness of MenB vaccines and willingness to vaccinate their teens with MenB vaccines compared to MenACWY vaccines, which have been routinely recommended for many years.

METHODS

We surveyed parents of teens attending high school in 2017-18 during the Minnesota State Fair. Parents reported via iPad their knowledge of and concern about meningococcal disease and their awareness of and willingness to vaccinate with MenB and MenACWY vaccines. We assessed the relationship between meningococcal disease knowledge and concern, MenB and MenACWY vaccine awareness, and willingness to vaccinate with MenB and MenACWY using adjusted logistic regression.

RESULTS

Among 445 parents, the majority had not heard of the newly introduced MenB vaccines Bexsero® (80.0%; 95% CI: 76.0-83.6) or Trumenba® (82.0%; 95% CI: 78.1-85.5) or the MenACWY vaccines Menactra® or Menveo® (68.8%; 95% CI: 64.2-73.0). The majority were at least somewhat willing to vaccinate their teen with MenB vaccine (89.6%; 95% CI: 86.5, 92.3) and MenACWY vaccine (91.2%; 95% CI: 88.2, 93.7). Awareness of MenB vaccines (OR: 3.8; 95% CI: 1.2-12.2) and concern about meningococcal disease (OR: 3.1; 95% CI: 1.5-6.3) were significantly associated with willingness to vaccinate with MenB vaccine.

CONCLUSIONS

Awareness of MenB vaccine is lacking among parents of teens but is an important predictor of willingness to vaccinate with the newly licensed MenB vaccines.

摘要

背景

在美国,脑膜炎 B 型(MenB)疫苗于 2014 年首次获得许可。2015 年,免疫实践咨询委员会建议青少年的父母与其提供者讨论接种 MenB 疫苗,而不是常规推荐。我们评估了父母对 MenB 疫苗的认识以及接种 MenB 疫苗的意愿,与多年来常规推荐的 MenACWY 疫苗相比。

方法

我们在 2017-18 年明尼苏达州博览会上调查了高中青少年的父母。父母通过 iPad 报告了他们对脑膜炎球菌病的了解和关注,以及对 MenB 和 MenACWY 疫苗的了解和接种意愿。我们使用调整后的逻辑回归评估了脑膜炎球菌病知识和关注、MenB 和 MenACWY 疫苗意识与接种 MenB 和 MenACWY 疫苗的意愿之间的关系。

结果

在 445 名父母中,大多数人没有听说过新引入的 MenB 疫苗 Bexsero®(80.0%;95%CI:76.0-83.6)或 Trumenba®(82.0%;95%CI:78.1-85.5)或 MenACWY 疫苗 Menactra®或 Menveo®(68.8%;95%CI:64.2-73.0)。大多数父母至少对为孩子接种 MenB 疫苗(89.6%;95%CI:86.5,92.3)和 MenACWY 疫苗(91.2%;95%CI:88.2,93.7)持一定程度的意愿。对 MenB 疫苗的认识(OR:3.8;95%CI:1.2-12.2)和对脑膜炎球菌病的关注(OR:3.1;95%CI:1.5-6.3)与接种 MenB 疫苗的意愿显著相关。

结论

青少年父母对 MenB 疫苗的认识不足,但这是他们愿意接种新获得许可的 MenB 疫苗的重要预测因素。

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